[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Cerebral dysfunctions caused by sepsis during ageing

T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection

JV Desai, D Kumar, T Freiwald, D Chauss… - Cell, 2023 - cell.com
Systemic candidiasis is a common, high-mortality, nosocomial fungal infection.
Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …

Gut mycobiota in immunity and inflammatory disease

XV Li, I Leonardi, ID Iliev - Immunity, 2019 - cell.com
The mammalian intestine is colonized by a wealth of microorganisms—including bacteria,
viruses, protozoa, and fungi—that are all integrated into a functional trans-kingdom …

Mutations in G protein–coupled receptors: mechanisms, pathophysiology and potential therapeutic approaches

T Schöneberg, I Liebscher, P Insel - Pharmacological reviews, 2021 - Elsevier
There are approximately 800 annotated G protein–coupled receptor (GPCR) genes, making
these membrane receptors members of the most abundant gene family in the human …

Fractalkine (CX3CL1) and its receptor CX3CR1: a promising therapeutic target in chronic kidney disease?

S Cormican, MD Griffin - Frontiers in immunology, 2021 - frontiersin.org
Innate immune cells are key contributors to kidney inflammation and fibrosis. Infiltration of
the renal parenchyma by innate immune cells is governed by multiple signalling pathways …

Exploiting antifungal immunity in the clinical context

MS Lionakis - Seminars in immunology, 2023 - Elsevier
The continuous expansion of immunocompromised patient populations at-risk for
develo** life-threatening opportunistic fungal infections in recent decades has helped …

Advances in understanding human genetic variations that influence innate immunity to fungi

RM Merkhofer, BS Klein - Frontiers in cellular and infection …, 2020 - frontiersin.org
Fungi are ubiquitous. Yet, despite our frequent exposure to commensal fungi of the normal
mammalian microbiota and environmental fungi, serious, systemic fungal infections are rare …

Circulating inflammation markers and prostate cancer

H Ugge, MK Downer, J Carlsson, M Bowden… - The …, 2019 - Wiley Online Library
Background Chronic inflammation is thought to influence the risk of prostate cancer. The
purpose of this population‐based case‐control study was to evaluate the association of 48 …