Utilizing non-coding RNA-mediated regulation of ATP binding cassette (ABC) transporters to overcome multidrug resistance to cancer chemotherapy

KKW To, Z Huang, H Zhang, CR Ashby Jr, L Fu - Drug Resistance Updates, 2024 - Elsevier
Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …

Advancing miRNA cancer research through artificial intelligence: from biomarker discovery to therapeutic targeting

R Aswathy, VA Chalos, K Suganya, S Sumathi - Medical Oncology, 2024 - Springer
MicroRNAs (miRNAs), a class of small non-coding RNAs, play a vital role in regulating gene
expression at the post-transcriptional level. Their discovery has profoundly impacted …

Identification and characterization of host miRNAs that target the mouse mammary tumour virus (MMTV) genome

B Gull, W Ahmad, J Baby, NG Panicker… - Open …, 2024 - royalsocietypublishing.org
The intricate interplay between viruses and hosts involves microRNAs (miRNAs) to regulate
gene expression by targeting cellular/viral messenger RNAs (mRNAs). Mouse mammary …

Revealing miRNAs patterns by employing matrix representations and energy analysis

K Sarapata, A Kania - Journal of Molecular Graphics and Modelling, 2024 - Elsevier
MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression.
Despite their relatively short length (about 21 nucleotides), they can regulate thousands of …

Exosomes from SHED-MSC regulate polarization and stress oxidative indexes in THP-1 derived M1 macrophages

A Fallah, AH Colagar, A Khosravi, M Saeidi - Archives of Biochemistry and …, 2024 - Elsevier
Objective The inhibition of M1 macrophages may be interesting for targeted therapy with
mesenchymal stem cell-derived Exosomes (MSC-EXOs). This study aimed to investigate the …