[HTML][HTML] Understanding the role of sex hormones in Cardiovascular kidney metabolic syndrome: toward personalized therapeutic approaches

M Guldan, S Unlu, SM Abdel-Rahman, L Ozbek… - Journal of clinical …, 2024 - mdpi.com
Cardiovascular kidney metabolic (CKM) syndrome represents a complex interplay of
cardiovascular disease (CVD), chronic kidney disease (CKD), and metabolic comorbidities …

Sex-specific epigenetic programming in renal fibrosis and inflammation

P Kumar, HL Brooks - American Journal of Physiology …, 2023 - journals.physiology.org
The growing prevalence of hypertension, heart disease, diabetes, and obesity along with an
aging population is leading to a higher incidence of renal diseases in society. Chronic …

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes …

M Scholz, K Horn, J Pott, M Wuttke, A Kühnapfel… - Nature …, 2024 - nature.com
X-chromosomal genetic variants are understudied but can yield valuable insights into
sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry …

Renal hypoxic reperfusion injury-on-chip model for studying combinational vitamin therapy

AR Chethikkattuveli Salih, A Asif… - ACS Biomaterials …, 2022 - ACS Publications
Renal ischemic-reperfusion injury decreases the chances of long-term kidney graft survival
and may lead to the loss of a transplanted kidney. During organ excision, the cycle of warm …

[HTML][HTML] Sex dimorphism in kidney health and disease: mechanistic insights and clinical implication

S Steiger, L Li, A Bruchfeld, KI Stevens, SM Moran… - Kidney International, 2024 - Elsevier
Sex is a key variable in the regulation of human physiology and pathology. Many diseases
disproportionately affect one sex: autoimmune diseases, such as systemic lupus …

The lower limit of reference of urinary albumin/creatinine ratio and the risk of chronic kidney disease progression in patients with type 2 diabetes mellitus

WH Tang, WC Hung, CP Wang, CC Wu… - Frontiers in …, 2022 - frontiersin.org
A urine albumin/creatinine ratio (UACR)< 30 mg/g is considered to be normal, while
increased risk of incident hypertension and cardiovascular disease mortality in subjects with …

[HTML][HTML] Sex and gender differences in liver fibrosis: pathomechanisms and clinical outcomes

M Jamalinia, A Lonardo, R Weiskirchen - Fibrosis, 2024 - sciepublish.com
The accumulation of extracellular matrix proteins is the hallmark of liver fibrosis associated
with all chronic liver disease (CLD) types. Liver fibrosis results from repeated bouts of liver …

Neuroimmunoendocrine link between chronic kidney disease and olfactory deficits

R Corona, B Ordaz, L Robles-Osorio… - Frontiers in Integrative …, 2022 - frontiersin.org
Chronic kidney disease (CKD) is a multifactorial pathology that progressively leads to the
deterioration of metabolic functions and results from deficient glomerular filtration and …

Associations between sleep-disordered breathing and serum uric acid and their sex differences: the Nagahama Study

H Sunadome, K Murase, Y Tabara, T Matsumoto… - Nutrients, 2023 - mdpi.com
Sleep-disordered breathing (SDB) is often accompanied by noncommunicable diseases
(NCDs), including gout. However, the association between serum uric acid (sUA) levels and …

Low Testosterone Level and Risk of Adverse Clinical Events among Male Patients with Chronic Kidney Disease: A Systematic Review and Meta‐Analysis of Cohort …

L Li, H Ju, H **, H Chen, M Sun… - Journal of Healthcare …, 2022 - Wiley Online Library
The phenomenon of low testosterone level is extremely common in male patients with
chronic kidney diseases (CKDs). This meta‐analysis aimed to evaluate whether the low …