Immunomodulatory properties of CD38 antibodies and their effect on anticancer efficacy in multiple myeloma

K Bisht, T Fukao, M Chiron, P Richardson… - Cancer …, 2023 - Wiley Online Library
Background CD38 has been established as an important therapeutic target for multiple
myeloma (MM), for which two CD38 antibodies are currently approved—daratumumab and …

Immune dysregulation in multiple myeloma: the current and future role of cell-based immunotherapy

BM Russell, DE Avigan - International Journal of Hematology, 2023 - Springer
Immune dysregulation is a hallmark of clinically active multiple myeloma (MM). Interactions
between malignant clonal cells and immune cells within the bone marrow microenvironment …

Concomitant 1q+ and t (4; 14) influences disease characteristics, immune system, and prognosis in double-hit multiple myeloma

M Ozga, Q Zhao, L Huric, C Miller, A Rosko… - Blood Cancer …, 2023 - nature.com
Dear editor, specific chromosomal abnormalities (CA) detected by Fluorescence in situ
hybridization (FISH), including translocation t (4; 14) and amplification or gain of …

Development and validation of an individualized and weighted Myeloma Prognostic Score System (MPSS) in patients with newly diagnosed multiple myeloma

X Mao, W Yan, D Mery, J Liu, H Fan… - American Journal of …, 2024 - Wiley Online Library
Current standard predictive models of disease risk do not adequately account for the
heterogeneity of survival outcomes in patients with new‐diagnosed multiple myeloma …