[HTML][HTML] Polyphenol-based hydrogels: Pyramid evolution from crosslinked structures to biomedical applications and the reverse design

Z Li, Z Chen, H Chen, K Chen, W Tao, X Ouyang… - Bioactive Materials, 2022 - Elsevier
As a kind of nature-derived bioactive materials, polyphenol-based hydrogels possess many
unique and outstanding properties such as adhesion, toughness, and self-healing due to …

Stimulus-responsive self-assembled prodrugs in cancer therapy

X Dong, RK Brahma, C Fang, SQ Yao - Chemical science, 2022 - pubs.rsc.org
Small-molecule prodrugs have become the main toolbox to improve the unfavorable
physicochemical properties of potential therapeutic compounds in contemporary anti-cancer …

Molecular bottlebrush prodrugs as mono-and triplex combination therapies for multiple myeloma

A Detappe, HVT Nguyen, Y Jiang, MP Agius… - Nature …, 2023 - nature.com
Cancer therapies often have narrow therapeutic indexes and involve potentially suboptimal
combinations due to the dissimilar physical properties of drug molecules. Nanomedicine …

Nanoparticulation of prodrug into medicines for cancer therapy

Y Zhang, H Cui, R Zhang, H Zhang… - Advanced …, 2021 - Wiley Online Library
This article provides a broad spectrum about the nanoprodrug fabrication advances co‐
driven by prodrug and nanotechnology development to potentiate cancer treatment. The …

Stimuli-responsive prodrug-based cancer nanomedicine

A **e, S Hanif, J Ouyang, Z Tang, N Kong, NY Kim… - …, 2020 - thelancet.com
The rapid development of nanotechnology results in the emergence of nanomedicines, but
the effective delivery of drugs to tumor sites remains a great challenge. Prodrug-based …

Cancer‐cell‐biomimetic nanoparticles for targeted therapy of multiple myeloma based on bone marrow homing

Y Qu, B Chu, X Wei, Y Chen, Y Yang, D Hu… - Advanced …, 2022 - Wiley Online Library
Multiple myeloma (MM) is the second most common hematological malignancy. It is
characterized by abnormal transformation and uncontrolled clonal proliferation of malignant …

[HTML][HTML] Nanomedicines: redefining traditional medicine

W Lu, J Yao, X Zhu, Y Qi - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Nanomedicines offer nanoscale drug delivery system. They offer ways of promising drug
transportation, and address the issues of lack of targeting and permeability of traditional …

Bortezomib-encapsulated CuS/carbon dot nanocomposites for enhanced photothermal therapy via stabilization of polyubiquitinated substrates in the proteasomal …

Y Yu, M Song, C Chen, Y Du, C Li, Y Han, F Yan… - ACS …, 2020 - ACS Publications
Photothermal therapy (PTT) is an emerging therapeutic strategy in the treatment of cancer;
however, a critical challenge remains in the rational design of synergistic nanoparticles as a …

Brain‐targeting drug delivery systems

P Liu, C Jiang - Wiley Interdisciplinary Reviews: Nanomedicine …, 2022 - Wiley Online Library
Brain diseases, including neurodegenerative diseases, acute ischemic stroke and brain
tumors, have become a major health problem and a huge burden on society with high …

[HTML][HTML] Cell membrane-cloaked nanotherapeutics for targeted drug delivery

NH Lee, S You, A Taghizadeh, M Taghizadeh… - International Journal of …, 2022 - mdpi.com
Cell membrane cloaking technique is bioinspired nanotechnology that takes advantage of
naturally derived design cues for surface modification of nanoparticles. Unlike modification …