3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

The ECM: to scaffold, or not to scaffold, that is the question

JC Valdoz, BC Johnson, DJ Jacobs, NA Franks… - International journal of …, 2021 - mdpi.com
The extracellular matrix (ECM) has pleiotropic effects, ranging from cell adhesion to cell
survival. In tissue engineering, the use of ECM and ECM-like scaffolds has separated the …

Activated PMN exosomes: pathogenic entities causing matrix destruction and disease in the lung

KR Genschmer, DW Russell, C Lal, T Szul, PE Bratcher… - Cell, 2019 - cell.com
Here, we describe a novel pathogenic entity, the activated PMN (polymorphonuclear
leukocyte, ie, neutrophil)-derived exosome. These CD63+/CD66b+ nanovesicles acquire …

One-dimensional titanium dioxide nanomaterials: nanotubes

K Lee, A Mazare, P Schmuki - Chemical reviews, 2014 - ACS Publications
In 1991, Iijima reported on the formation of carbon nanotubes (1) using a simple arc
discharge reaction that led to an arrangement of the material in some micrometer long tubes …

Multicomponent peptide assemblies

DM Raymond, BL Nilsson - Chemical Society Reviews, 2018 - pubs.rsc.org
Self-assembled peptide nanostructures have been increasingly exploited as functional
materials for applications in biomedicine and energy. The emergent properties of these …

[HTML][HTML] The overview of porous, bioactive scaffolds as instructive biomaterials for tissue regeneration and their clinical translation

G Lutzweiler, A Ndreu Halili, N Engin Vrana - Pharmaceutics, 2020 - mdpi.com
Porous scaffolds have been employed for decades in the biomedical field where
researchers have been seeking to produce an environment which could approach one of …

Engineering alginate as bioink for bioprinting

J Jia, DJ Richards, S Pollard, Y Tan, J Rodriguez… - Acta biomaterialia, 2014 - Elsevier
Recent advances in three-dimensional (3-D) printing offer an excellent opportunity to
address critical challenges faced by current tissue engineering approaches. Alginate …

3D printing of layered brain-like structures using peptide modified gellan gum substrates

R Lozano, L Stevens, BC Thompson, KJ Gilmore… - Biomaterials, 2015 - Elsevier
The brain is an enormously complex organ structured into various regions of layered tissue.
Researchers have attempted to study the brain by modeling the architecture using two …

Enzyme-catalyzed crosslinkable hydrogels: emerging strategies for tissue engineering

LSM Teixeira, J Feijen, CA van Blitterswijk, PJ Dijkstra… - Biomaterials, 2012 - Elsevier
State-of-the-art bioactive hydrogels can easily and efficiently be formed by enzyme-
catalyzed mild-crosslinking reactions in situ. Yet this cell-friendly and substrate-specific …

The interaction of cells and bacteria with surfaces structured at the nanometre scale

K Anselme, P Davidson, AM Popa, M Giazzon, M Liley… - Acta biomaterialia, 2010 - Elsevier
The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …