The present review sets out to discuss recent developments of the effects and mechanisms
of carrier properties on their circulation time. For most drugs, sufficient in vivo circulation time …

Long acting injectable formulations have been developed to sustain the action of drugs in
the body over desired periods of time. These delivery platforms have been utilized for both …

Hepatocellular carcinoma (HCC) has been known as the second common leading cancer
worldwide, as it responds poorly to both chemotherapy and medication. Triptolide (TP), a …

Poly (lactic-co-glycolic acid)(PLGA) is one of the preferred polymeric inactive ingredients for
long-acting parenteral drug products that are constituted of complex formulations. Despite …

Abstract Adopting the Quality by Design (QbD) approach in the drug development process
has transformed from “nice-to-do” into a crucial and required part of the development …

Hepatocellular carcinoma (HCC) has become the fourth predominant cause of cancer-
related deaths worldwide, and HCC is still one of the worst prognoses for survival as it is …

Background Inflammation serves as our body's immune response to combat infections,
pathogens, viruses, and external stimuli. Inflammation can be classified into two types: acute …

Therapeutics based on proteins and peptides have profoundly transformed the landscape of
treatment for diseases, from diabetes mellitus to cancers, yet the short half-life and low …

Therapeutic leukaemia vaccines have shown modest potency. Here, we show that the co-
encapsulation of a leukaemia-associated epitope peptide highly expressed in leukaemia …

Recent work has highlighted the potential of puerarin (PU) as a valuable compound to treat
Parkinson's disease (PD), but its undesirable water solubility and bioavailability have …