Substance and energy metabolism are the basis for all life activities and are largely
regulated by cell-to-cell communication. Microbial cell-to-cell communication often occurs by …

Escherichia coli is a Gram-negative commensal bacterium of the normal microbiota of
humans and animals. However, several E. coli strains are opportunistic pathogens …

Klebsiella pneumoniae is a Gram-negative pathogen that has become a worldwide concern
due to the emergence of multidrug-resistant isolates responsible for various invasive …

Bacteria live in complex polymicrobial communities and are constantly competing for
resources. The type VI secretion system (T6SS) is a widespread antagonistic mechanism …

The type VI secretion system (T6SS) is a multiprotein complex widespread in Proteobacteria
and dedicated to the delivery of toxins into both prokaryotic and eukaryotic cells. It thus …

Bacteria can coordinate behavior in response to population density through the production,
release, and detection of small molecules, a phenomenon known as quorum sensing …

The acid tolerance mechanism is important for Escherichia coli to resist acidic conditions
encountered in mammalian host digestive tract environment. Here, we explored how the …

Cronobacter sakazakii is a common foodborne pathogen, and the mortality rate of its
infection is as high as 40–80%. SdiA acts as a quorum sensing regulator in many foodborne …

Complex inter-bacterial interactions largely influence the structure and function of the gut
microbial community. Though several host-associated phenomena have often been shown …

Conjugation is a key mechanism for horizontal gene transfer and plays an important role in
bacterial evolution, especially with respect to antibiotic resistance. However, little is known …