Cognitive function in humans depends on the complex and interplay between multiple body
systems, including the hypothalamic-pituitary-adrenal (HPA) axis. The gut microbiota, which …

Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a
chronic and relapsing inflammatory disorder of the intestine. Although its incidence is …

Methods capable of maintaining gut microbiota homeostasis to prevent bacterial
translocation and infection under external threats are critical for multiple facets of human …

The gut microbiota modulates immune processes both locally and systemically. This
includes whether and how the immune system reacts to emerging tumours, whether …

A number of mechanisms ensure that the intestine is protected from pathogens and also
against our own intestinal microbiota. The outermost of these is the secreted mucus, which …

The gut microbiome (GM) has been implicated in a vast number of human pathologies and
has become a focus of oncology research over the past 5 years. The normal gut microbiota …

The gut microbiome significantly influences immune responses and the efficacy of immune
checkpoint inhibitors. We conducted a clinical trial (NCT04264975) combining an anti …

Abstract Coronavirus disease 19 (COVID-19) is a pandemic condition caused by the new
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …

Gut microbiota dysbiosis has been observed in a number of autoimmune diseases.
However, the role of the gut microbiota in systemic lupus erythematosus (SLE), a …

Immune-checkpoint inhibitors (ICI) now represent the standard of care for several cancer
types. In pre-clinical models, absence of an intact gut microbiome negatively impacted ICI …