Centrifugal microfluidic platforms: advanced unit operations and applications

O Strohmeier, M Keller, F Schwemmer… - Chemical Society …, 2015‏ - pubs.rsc.org
Centrifugal microfluidics has evolved into a mature technology. Several major diagnostic
companies either have products on the market or are currently evaluating centrifugal …

Immobilization of antibodies and enzymes on 3-aminopropyltriethoxysilane-functionalized bioanalytical platforms for biosensors and diagnostics

SK Vashist, E Lam, S Hrapovic, KB Male… - Chemical …, 2014‏ - ACS Publications
Biosensing and diagnostic platforms with high sensitivity, specificity, and fast response time
are based on immobilized biomolecules such as antibodies (Abs), aptamers, enzymes …

A review on recent developments for biomolecule separation at analytical scale using microfluidic devices

KKR Tetala, MA Vijayalakshmi - Analytica chimica acta, 2016‏ - Elsevier
Microfluidic devices with their inherent advantages like the ability to handle 10− 9 to 10− 18
L volume, multiplexing of microchannels, rapid analysis and on-chip detection are proving to …

Direct covalent biomolecule immobilization on plasma-nanotextured chemically stable substrates

K Tsougeni, PS Petrou, K Awsiuk… - … Applied Materials & …, 2015‏ - ACS Publications
A new method for direct covalent immobilization of protein molecules (including antibodies)
on organic polymers with plasma-induced random micronanoscale topography and stable …

Frequency shift of a SH-SAW biosensor with glutaraldehyde and 3-aminopropyltriethoxysilane functionalized films for detection of epidermal growth factor

XC Lo, JY Li, MT Lee, DJ Yao - Biosensors, 2020‏ - mdpi.com
The frequency shift of a shear-horizontal surface-acoustic-wave (SH-SAW) biosensor in
which the concentration of biomolecule is determined by the amount of its adsorption on the …

At-line bioprocess monitoring by immunoassay with rotationally controlled serial siphoning and integrated supercritical angle fluorescence optics

CE Nwankire, GG Donohoe, X Zhang, J Siegrist… - Analytica chimica …, 2013‏ - Elsevier
In this paper we report a centrifugal microfluidic “lab-on-a-disc” system for at-line monitoring
of human immunoglobulin G (hIgG) in a typical bioprocess environment. The novelty of this …

[HTML][HTML] Quantification of impedance and mechanical properties of Zeonor using scanning acoustic microscopy

S Ojha, K Agarwal, A Shelke, A Habib - Applied Acoustics, 2024‏ - Elsevier
This article explores the potential of Zeonor, a transparent cyclic olefin polymer, for
applications in transparent acoustic/photo-acoustic transducers. Despite its widespread use …

Spin coating of hydrophilic polymeric films for enhanced centrifugal flow control by serial siphoning

M Kitsara, CE Nwankire, L Walsh, G Hughes… - Microfluidics and …, 2014‏ - Springer
In this paper, we implement rotational flow control on a polymeric microfluidic “lab-on-a-disc”
platform by combining serial siphoning and capillary valving for sequential release of a set …

Fabricating a cycloolefin polymer immunoassay platform with a dual-function polymer brush via a surface-initiated photoiniferter-mediated polymerization strategy

J Ma, S Luan, L Song, J **, S Yuan… - … Applied Materials & …, 2014‏ - ACS Publications
The development of technologies for a biomedical detection platform is critical to meet the
global challenges of various disease diagnoses. In this study, an inert cycloolefin polymer …

Molecular separation by using active and passive microfluidic chip designs: a comprehensive review

A Ebrahimi, K Icoz, R Didarian, CH Shih… - Advanced Materials …, 2024‏ - Wiley Online Library
Separation and identification of molecules and biomolecules such as nucleic acids, proteins,
and polysaccharides from complex fluids are known to be important due to unmet needs in …