Update in global trends and aetiology of hepatocellular carcinoma

P Rawla, T Sunkara, P Muralidharan… - Contemporary Oncology …, 2018 - termedia.pl
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver responsible
for an increasing number of cancer-related deaths, especially in develo** economies of …

The impact of oxidative DNA damage and stress on telomere homeostasis

RP Barnes, E Fouquerel, PL Opresko - Mechanisms of ageing and …, 2019 - Elsevier
Telomeres are dynamic nucleoprotein-DNA structures that cap and protect linear
chromosome ends. Because telomeres shorten progressively with each replication, they …

Arsenic and human health effects: A review

KSM Abdul, SS Jayasinghe, EPS Chandana… - Environmental …, 2015 - Elsevier
Arsenic (As) is ubiquitous in nature and humans being exposed to arsenic via atmospheric
air, ground water and food sources are certain. Major sources of arsenic contamination …

The association between stressors and telomeres in non‐human vertebrates: a meta‐analysis

M Chatelain, SM Drobniak, M Szulkin - Ecology letters, 2020 - Wiley Online Library
Animal response to stressors such as harsh environmental conditions and demanding
biological processes requires energy generated through increased mitochondrial activity …

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

WH Goodson III, L Lowe, DO Carpenter… - …, 2015 - academic.oup.com
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide,
but credible estimates from the World Health Organization and the International Agency for …

Brain-skin connection: stress, inflammation and skin aging

Y Chen, J Lyga - … & Allergy-Drug Targets (Formerly Current …, 2014 - ingentaconnect.com
The intricate relationship between stress and skin conditions has been documented since
ancient times. Recent clinical observations also link psychological stress to the onset or …

Causes of genome instability: the effect of low dose chemical exposures in modern society

SAS Langie, G Koppen, D Desaulniers… - …, 2015 - academic.oup.com
Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Oxidative potential and inflammatory impacts of source apportioned ambient air pollution in Bei**g

Q Liu, J Baumgartner, Y Zhang, Y Liu… - … science & technology, 2014 - ACS Publications
Air pollution exposure is associated with a range of adverse health impacts. Knowledge of
the chemical components and sources of air pollution most responsible for these health …

[HTML][HTML] BDE-209 and DBDPE induce male reproductive toxicity through telomere-related cell senescence and apoptosis in SD rat

X Li, J Liu, G Zhou, Y Sang, Y Zhang, L **g, Z Shi… - Environment …, 2021 - Elsevier
Abstract Decabrominated diphenyl ether (BDE-209) and decabromodiphenyl ethane
(DBDPE) are common flame retardants utilized in many kinds of electronic and textile …

Telomeropathies: An emerging spectrum disorder

B Holohan, WE Wright, JW Shay - Journal of Cell Biology, 2014 - rupress.org
A constellation of related genetic diseases are caused by defects in the telomere
maintenance machinery. These disorders, often referred to as telomeropathies, share …