Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
The Fanconi anemia pathway in cancer
Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure
(BMF), congenital defects, inability to repair DNA interstrand cross-links (ICLs), and cancer …
(BMF), congenital defects, inability to repair DNA interstrand cross-links (ICLs), and cancer …
The Fanconi anaemia pathway: new players and new functions
The Fanconi anaemia pathway repairs DNA interstrand crosslinks (ICLs) in the genome. Our
understanding of this complex pathway is still evolving, as new components continue to be …
understanding of this complex pathway is still evolving, as new components continue to be …
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
POLQ is a key effector of DSB repair by microhomology-mediated end-joining (MMEJ) and is
overexpressed in many cancers. POLQ inhibitors confer synthetic lethality in HR and …
overexpressed in many cancers. POLQ inhibitors confer synthetic lethality in HR and …
Fanconi anemia: current insights regarding epidemiology, cancer, and DNA repair
Fanconi anemia is a genetic disorder that is characterized by bone marrow failure, as well
as a predisposition to malignancies including leukemia and squamous cell carcinoma …
as a predisposition to malignancies including leukemia and squamous cell carcinoma …
Fanconi anaemia and cancer: an intricate relationship
Fanconi anaemia (FA) is a genetic disorder that is characterized by bone marrow failure
(BMF), developmental abnormalities and predisposition to cancer. Together with other …
(BMF), developmental abnormalities and predisposition to cancer. Together with other …
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells
Haematopoietic stem cells renew blood. Accumulation of DNA damage in these cells
promotes their decline, while misrepair of this damage initiates malignancies. Here we …
promotes their decline, while misrepair of this damage initiates malignancies. Here we …
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response
Endogenous DNA damage can perturb transcription, triggering a multifaceted cellular
response that repairs the damage, degrades RNA polymerase II and shuts down global …
response that repairs the damage, degrades RNA polymerase II and shuts down global …
Causes and consequences of replication stress
MK Zeman, KA Cimprich - Nature cell biology, 2014 - nature.com
Replication stress is a complex phenomenon that has serious implications for genome
stability, cell survival and human disease. Generation of aberrant replication fork structures …
stability, cell survival and human disease. Generation of aberrant replication fork structures …
DNA damage and associated DNA repair defects in disease and premature aging
Genetic information is constantly being attacked by intrinsic and extrinsic damaging agents,
such as reactive oxygen species, atmospheric radiation, environmental chemicals, and …
such as reactive oxygen species, atmospheric radiation, environmental chemicals, and …
Human hematopoietic stem cell vulnerability to ferroptosis
Hematopoietic stem cells (HSCs) have a number of unique physiologic adaptations that
enable lifelong maintenance of blood cell production, including a highly regulated rate of …
enable lifelong maintenance of blood cell production, including a highly regulated rate of …