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Recent advancement in understanding of Alzheimer's disease: Risk factors, subtypes, and drug targets and potential therapeutics
Alzheimer's disease (AD) is a significant neocortical degenerative disorder characterized by
the progressive loss of neurons and secondary alterations in white matter tracts …
the progressive loss of neurons and secondary alterations in white matter tracts …
Cuproptosis and Cu: a new paradigm in cellular death and their role in non-cancerous diseases
Z Yang, R Feng, H Zhao - Apoptosis, 2024 - Springer
Cuproptosis, a newly characterized form of regulated cell death driven by copper
accumulation, has emerged as a significant mechanism underlying various non-cancerous …
accumulation, has emerged as a significant mechanism underlying various non-cancerous …
Heavy metals exposure and Alzheimer's disease: Underlying mechanisms and advancing therapeutic approaches
NA Althobaiti - Behavioural Brain Research, 2024 - Elsevier
Heavy metals such as lead, cadmium, mercury, and arsenic are prevalent in the
environment due to both natural and anthropogenic sources, leading to significant public …
environment due to both natural and anthropogenic sources, leading to significant public …
Molecular interactions, structural effects, and binding affinities between silver ions (Ag+) and amyloid beta (Aβ) peptides
Because silver is toxic to microbes, but not considered toxic to humans, the metal has been
used as an antimicrobial agent since ancient times. Today, silver nanoparticles and colloidal …
used as an antimicrobial agent since ancient times. Today, silver nanoparticles and colloidal …
Targeting biometals in Alzheimer's disease with metal chelating agents including coumarin derivatives
A Gucký, S Hamuľaková - CNS drugs, 2024 - Springer
Numerous physiological processes happening in the human body, including cerebral
development and function, require the participation of biometal ions such as iron, copper …
development and function, require the participation of biometal ions such as iron, copper …
Zeolite and neurodegenerative diseases
S Panaiotov, L Tancheva, R Kalfin, P Petkova-Kirova - Molecules, 2024 - mdpi.com
Neurodegenerative diseases (NDs), characterized by progressive degeneration and death
of neurons, are strongly related to aging, and the number of people with NDs will continue to …
of neurons, are strongly related to aging, and the number of people with NDs will continue to …
Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies
As the world population ages, there will be an increasing need for effective therapies for
aging‐associated neurodegenerative disorders, which remain untreatable. Dementia due to …
aging‐associated neurodegenerative disorders, which remain untreatable. Dementia due to …
Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials
D Huang, W Liao, J Li, T Chen, X Wang… - Advanced Functional …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that
constitutes the third most common cause of death among elderly individuals. AD patients …
constitutes the third most common cause of death among elderly individuals. AD patients …
Nanomedicine targets endogenous copper ions for disease diagnosis and therapy
X Li, Y Cui, T Zhou, J Li, P Lu, L Yuwen, L Wang… - Chemical Engineering …, 2023 - Elsevier
Copper ion is an essential microelement that plays vital roles in a wide range of
physiological processes, and aberrant copper levels in vivo usually cause various diseases …
physiological processes, and aberrant copper levels in vivo usually cause various diseases …
[HTML][HTML] Bioinorganic chemistry of micronutrients related to Alzheimer's and Parkinson's diseases
A Kola, F Nencioni, D Valensin - Molecules, 2023 - mdpi.com
Metal ions are fundamental to guarantee the regular physiological activity of the human
organism. Similarly, vitamins play a key role in many biological functions of the metabolism …
organism. Similarly, vitamins play a key role in many biological functions of the metabolism …