Over the past several decades, the incidence of bacterial meningitis in children has
decreased but there remains a significant burden of disease in adults, with a mortality of up …

Summary Non-typeable Haemophilus influenzae (NTHi) is a major cause of mucosal
infections such as otitis media, sinusitis, conjunctivitis, and exacerbations of chronic …

Haemophilus influenzae serotype b (Hib) was previously the most common cause of
bacterial meningitis and an important etiologic agent of pneumonia in children aged< 5 …

The incidence of severe Haemophilus influenza infections, such as sepsis and meningitis,
has declined substantially since the introduction of the H. influenzae serotype b vaccine …

Importance The impact of vaccination, antibiotics, and anti-inflammatory treatment on
pathogen distribution and outcome of bacterial meningitis over the past century is uncertain …

Haemophilus influenzae, particularly H influenzae serotype b (Hib), is an important
pathogen that causes serious diseases like meningitis and septicaemia. Since the …

The human-restricted bacterium Haemophilus influenzae is responsible for respiratory
infections in both children and adults. While colonization begins in the upper airways, it can …

Background Haemophilus influenzae type b (Hib) vaccine was introduced as a voluntary
vaccine in December 2008 and was included in the national routine immunization program …

The rapid, accurate, and efficient identification of an infectious disease is critical to ensure
timely clinical treatment and prevention in public health settings. In 2015, meningitis caused …

Background More than two decades after the implementation of the Hib conjugate vaccine in
North America, Haemophilus influenzae serotype a (Hia) has emerged as a significant …