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Generative modeling and latent space arithmetics predict single-cell perturbation response across cell types, studies and species
Accurately modeling cellular response to perturbations is a central goal of computational
biology. While such modeling has been proposed based on statistical, mechanistic and …
biology. While such modeling has been proposed based on statistical, mechanistic and …
Batch effect removal via batch-free encoding
U Shaham - BioRxiv, 2018 - biorxiv.org
Biological measurements often contain systematic errors, also known as “batch effects”,
which may invalidate downstream analysis when not handled correctly. The problem of …
which may invalidate downstream analysis when not handled correctly. The problem of …
Correcting nuisance variation using Wasserstein distance
Profiling cellular phenotypes from microscopic imaging can provide meaningful biological
information resulting from various factors affecting the cells. One motivating application is …
information resulting from various factors affecting the cells. One motivating application is …
Correcting nuisance variation using wasserstein distance
Profiling cellular phenotypes from microscopic imaging can provide meaningful biological
information resulting from various factors affecting the cells. One motivating application is …
information resulting from various factors affecting the cells. One motivating application is …
A new approach to batch effect removal based on distribution matching in latent space
Advanced measurement techniques such as genomics are capable of acquiring high-
throughput data in high dimensions, enabling new scientific discoveries, and offering unique …
throughput data in high dimensions, enabling new scientific discoveries, and offering unique …