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The gut–liver axis and gut microbiota in health and liver disease
CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …
Bile acids and the gut microbiota: metabolic interactions and impacts on disease
SL Collins, JG Stine, JE Bisanz, CD Okafor… - Nature Reviews …, 2023 - nature.com
Despite decades of bile acid research, diverse biological roles for bile acids have been
discovered recently due to developments in understanding the human microbiota. As …
discovered recently due to developments in understanding the human microbiota. As …
Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors
DQ Huang, P Mathurin, H Cortez-Pinto… - Nature reviews …, 2023 - nature.com
Heavy alcohol consumption is a major cause of morbidity and mortality. Globally, alcohol per-
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …
capita consumption rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to …
[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer
A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …
documented for a variety of cancer types with unclear biological functions. Here, we …
Gut–liver axis: barriers and functional circuits
The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …
microbiome, diet and other environmental factors. The sum of these interactions is …
Immunotherapies for hepatocellular carcinoma
JM Llovet, F Castet, M Heikenwalder… - Nature reviews Clinical …, 2022 - nature.com
Liver cancer, more specifically hepatocellular carcinoma (HCC), is the second leading
cause of cancer-related death and its incidence is increasing globally. Around 50% of …
cause of cancer-related death and its incidence is increasing globally. Around 50% of …
Imbalanced gut microbiota fuels hepatocellular carcinoma development by sha** the hepatic inflammatory microenvironment
KM Schneider, A Mohs, W Gui, EJC Galvez… - Nature …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide,
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …
Interaction between microbiota and immunity in health and disease
D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …
development and function includes multifold interactions in homeostasis and disease. The …
Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications
LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …
accumulating evidence has clarified the complex role of the human microbiota in the …
[PDF][PDF] Emerging immunotherapy for HCC: A guide for hepatologists
F Foerster, SJ Gairing, SI Ilyas, PR Galle - Hepatology, 2022 - Wiley Online Library
HCC is one of the most common cancers worldwide, and the third leading cause of cancer‐
related death globally. HCC comprises nearly 90% of all cases of primary liver cancer …
related death globally. HCC comprises nearly 90% of all cases of primary liver cancer …