Recent advances in synthesis and medicinal chemistry of benzodiazepines

N Arora, P Dhiman, S Kumar, G Singh, V Monga - Bioorganic Chemistry, 2020 - Elsevier
Benzodiazepines (BZDs) represent a diverse class of bicyclic heterocyclic molecules. In the
last few years, benzodiazepines have emerged as potential therapeutic agents. As a result …

Benzodiazepines: their use either as essential medicines or as toxics substances

E Sanabria, RE Cuenca, MÁ Esteso, M Maldonado - Toxics, 2021 - mdpi.com
This review highlights the nature, characteristics, properties, pharmacological differences
between different types of benzodiazepines, the mechanism of action in the central nervous …

Synthesis and characterization of versatile MgO–ZrO 2 mixed metal oxide nanoparticles and their applications

MB Gawande, PS Branco, K Parghi… - Catalysis Science & …, 2011 - pubs.rsc.org
A heterogeneous, versatile nano-magnesia-zirconia or MgO–ZrO2 (MZ) catalyst was
prepared by an ultra dilution method. The as-synthesised catalyst was characterized by …

Camphorsulfonic acid (CSA): An efficient organocatalyst for the synthesis or derivatization of heterocycles with biologically promising activities

G Kaur, K Bala, S Devi, B Banerjee - Current Green Chemistry, 2018 - ingentaconnect.com
Natural product modified organocatalysts have gained attention due to their environmentally
benign and biodegradable nature and as a result, these are now becoming powerful tools …

MgO-ZrO2 mixed nanocomposites: fabrication methods and applications

L Keerthana, C Sakthivel, I Prabha - Materials Today Sustainability, 2019 - Elsevier
Abstract In recent years, MgO-ZrO 2 composite has made a versatile progress in its
applications because of its outstanding resistance to temperature and corrosion. It was …

Solvent-Free syntheses of 1, 5-Benzodiazepines using HY Zeolite as a green solid acid catalyst

M Jeganathan, K Pitchumani - ACS Sustainable Chemistry & …, 2014 - ACS Publications
1, 5-Benzodiazepines are synthesized from 1, 2-diamines and ketones catalyzed by HY
zeolite at 50° C under solvent-free conditions. This process offers an easy and efficient …

Graphite oxide: a metal free highly efficient carbocatalyst for the synthesis of 1, 5-benzodiazepines under room temperature and solvent free heating conditions

R Jamatia, A Gupta, B Dam, M Saha, AK Pal - Green Chemistry, 2017 - pubs.rsc.org
Graphite Oxide (GO), an attractive metal free carbocatalyst, was employed as a green and
highly efficient catalytic system for the synthesis of 1, 5-benzodiazepines. The reaction was …

Design of novel catalysts for synthesis of 1, 5-benzodiazepines from 1, 2-phenylenediamine and ketones: NH2-MIL-101 (Al) as integrated structural scaffold for …

VI Isaeva, MN Timofeeva, VN Panchenko… - Journal of …, 2019 - Elsevier
Novel nanoporous composites (MIL/K-SO 3 H and MIL/Ks-CN) were synthesized by the
encapsulation of para-sulfonatocalix [4] arene (K-SO 3 H) and para-tert-butylthiacalix [4] …

A highly efficient and green method for the synthesis of 3, 4-dihydropyrimidin-2-ones and 1, 5-benzodiazepines catalyzed by dodecyl sulfonic acid in water

SD Sharma, P Gogoi, D Konwar - Green Chemistry, 2007 - pubs.rsc.org
A simple, efficient, mild and green method has been developed for the synthesis of 3, 4-
dihydropyrimidin-2-ones employing dodecyl sulfonic acid as an excellent surfactant-type …

Silica-supported NiO nanocomposites prepared via a sol–gel technique and their excellent catalytic performance for one-pot multicomponent synthesis of …

Z Nasir, A Ali, M Shakir, R Wahab - New Journal of Chemistry, 2017 - pubs.rsc.org
Heterogeneous and versatile NiO–SiO2 NCs were synthesized by a sol–gel technique and
used as a catalyst for the one-pot multicomponent synthesis of benzodiazepine derivatives …