The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Cancer is the second largest disease throughout the world with an increasing mortality rate
over the past few years. The patient's survival rate is uncertain due to the limitations of …

Leukemia often initiates following dysfunctions in hematopoietic stem cells lineages. Various
types of leukemia, including acute lymphoblastic leukemia (ALL), chronic myelogenous …

Iron metabolism and tumor biology are intimately linked. Iron facilitates the production of
oxygen radicals, which may either result in iron-induced cell death, ferroptosis, or contribute …

Quantum dots (QDs) are semiconductor nanocrystals possessing unique optoelectrical
properties in that they can emit light energy of specific tunable wavelengths when excited by …

The advent of nanotechnologies such as nanocarriers and nanotherapeutics has changed
the treatment strategy and developed a more efficacious novel drug delivery system. Various …

Introduction Fluorescence-guided surgery is one of the rapidly emerging methods of surgical
“theranostics.” In this review, we summarize current fluorescence techniques used in …

Glioblastoma (GBM) represents a formidable challenge in oncology, characterized by
aggressive proliferation and poor prognosis. Iron metabolism plays a critical player in GBM …

Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …

There is a broad range of biological, chemical and physical hurdles for drugs to reach the
brain. Nanoparticulate drug delivery systems hold tremendous potential for diagnosis and …