Emerging applications of high-precision Cu isotopic analysis by MC-ICP-MS

KV Sullivan, JA Kidder, TP Junqueira… - Science of The Total …, 2022 - Elsevier
As a component of many minerals and an essential trace element in most aerobic
organisms, the transition metal element Cu is important for studying reduction-oxidation …

Applications of zinc stable isotope analysis in environmental and biological systems: a review

TP Junqueira, B Vriens, MI Leybourne… - Geochemistry …, 2024 - lyellcollection.org
Zinc (Zn) is an essential trace element that is involved in both biotic and abiotic processes in
Earth's surface environments. Over the last 20 years, advances in mass spectrometry …

Cu, Fe, and Zn isotope ratios in murine Alzheimer's disease models suggest specific signatures of amyloidogenesis and tauopathy

N Solovyev, AH El-Khatib, M Costas-Rodríguez… - Journal of Biological …, 2021 - jbc.org
Alzheimer's disease (AD) is characterized by accumulation of tau and amyloid-beta in the
brain, and recent evidence suggests a correlation between associated protein aggregates …

The influence of physiological and lifestyle factors on essential mineral element isotopic compositions in the human body: implications for the design of isotope …

RET Moore, F Vanhaecke - Metallomics, 2023 - academic.oup.com
In the last 20 years, the application of high-precision isotopic analysis of essential mineral
elements (Mg, K, Ca, Fe, Cu, and Zn) to biomedicine (sometimes referred to as isotope …

Zinc stable isotopes in urine as diagnostic for cancer of secretory organs

K Schilling, RET Moore, MS Capper… - Metallomics, 2021 - academic.oup.com
Non-toxic bismuth salts are used in anti-ulcer medications and to protect against
nephrotoxicity from anticancer drugs. Bismuth salts also induce metallothionein (MT), a …

Zinc stable isotope analysis reveals Zn dyshomeostasis in benign tumours, breast cancer, and adjacent histologically normal tissue

RET Moore, MS Capper, K Schilling, K Goddard… - Metallomics, 2021 - academic.oup.com
The disruption of Zn homeostasis has been linked with breast cancer development and
progression. To enhance our understanding of changes in Zn homeostasis both inside and …

Reliable and precise Zn isotopic analysis of biological matrices using a fully automated dual-column purification procedure

A Retzmann, KA Miller, FAA Mohamed… - Analytical and …, 2024 - Springer
A fully automated dual-column purification procedure for Zn from biological samples,
designed for subsequent Zn isotopic analysis, is presented that utilizes the prep FAST MC™ …

[HTML][HTML] Serum Mg isotopic composition reveals that Mg dyshomeostasis remains in type 1 diabetes despite the resolution of hypomagnesemia

KV Sullivan, Y Assantuh, R Grigoryan… - International Journal of …, 2023 - mdpi.com
Hypomagnesemia was historically prevalent in individuals with type 1 diabetes mellitus
(T1DM), but contemporary results indicate an incidence comparable to that in the general …

Zinc Isotope Measurement by MC‐ICP‐MS in Geological Certified Reference Materials

J Wang, DM Tang, QH Yuan, BX Su… - Geostandards and …, 2023 - Wiley Online Library
Here we present an analytical method for Zinc (Zn) isotopic measurements using “standard‐
sample bracketing” on a Nu Sapphire multi‐collector inductively coupled plasma‐mass …

[PDF][PDF] Zinc stable isotope analysis reveals Zn dyshomeostasis in benign tumours, breast cancer, and

KV Sullivan, RET Moore, MS Capper, K Schilling… - 2021 - academia.edu
The disruption of Zn homeostasis has been linked with breast cancer development and
progression. To enhance our understanding of changes in Zn homeostasis both inside and …