Hybrid nanosystems for biomedical applications

J Seaberg, H Montazerian, MN Hossen… - ACS …, 2021 - ACS Publications
Inorganic/organic hybrid nanosystems have been increasingly developed for their versatility
and efficacy at overcoming obstacles not readily surmounted by nonhybridized counterparts …

[HTML][HTML] Advances in the synthesis and application of magnetic ferrite nanoparticles for cancer therapy

SR Mokhosi, W Mdlalose, A Nhlapo, M Singh - Pharmaceutics, 2022 - mdpi.com
Cancer is among the leading causes of mortality globally, with nearly 10 million deaths in
2020. The emergence of nanotechnology has revolutionised treatment strategies in …

[HTML][HTML] Lipid nanoparticles: promising treatment approach for Parkinson's disease

K Jagaran, M Singh - International Journal of Molecular Sciences, 2022 - mdpi.com
Parkinson's disease (PD), a neurodegenerative disorder, is a life-altering, debilitating
disease exhibiting a severe physical, psychological, and financial burden on patients …

Gold nanoparticles and cancer: Detection, diagnosis and therapy

S Medici, M Peana, D Coradduzza… - Seminars in cancer …, 2021 - Elsevier
Gold nanoparticles (AuNPS) represent one of the most studied classes of nanomaterials for
biomedical applications, especially in the field of cancer research. In fact, due to their unique …

Dendrimers as modifiers of inorganic nanoparticles for therapeutic delivery in cancer

M Zenze, A Daniels, M Singh - Pharmaceutics, 2023 - mdpi.com
The formulation of nanoscale systems with well-defined sizes and shapes is of great interest
in applications such as drug and gene delivery, diagnostics and imaging. Dendrimers are …

Composite materials based on chitosan/gold nanoparticles: From synthesis to biomedical applications

AB da Silva, KB Rufato, AC de Oliveira… - International Journal of …, 2020 - Elsevier
Conventional strategies (Turkevich's, and modified Turkevich's methods) often synthesize
gold nanoparticles (AuNPs). These pathways produce AuNPs using toxic chemistries to …

[HTML][HTML] Dendrimer-coated gold nanoparticles for efficient folate-targeted mRNA delivery in vitro

LS Mbatha, F Maiyo, A Daniels, M Singh - Pharmaceutics, 2021 - mdpi.com
Messenger RNA (mRNA) is not an attractive candidate for gene therapy due to its instability
and has therefore received little attention. Recent studies show the advantage of mRNA over …

[HTML][HTML] Bimetallic nanoparticles as suitable nanocarriers in cancer therapy

H Makada, S Habib, M Singh - Scientific African, 2023 - Elsevier
Cancer is a widespread disease which has been prevalent for decades and for which a cure
is yet to be discovered. Current treatments are fraught with severe side effects to patients …

[HTML][HTML] The potential of curcumin-capped nanoparticle synthesis in cancer therapy: a green synthesis approach

J Venkatas, A Daniels, M Singh - Nanomaterials, 2022 - mdpi.com
Cancer nanotherapeutics is an important field of research which utilizes nanomaterials as
an approach to cancer therapy. Nano-mediated therapeutic delivery systems overcome the …

[HTML][HTML] Folate-targeted mRNA delivery using chitosan-functionalized selenium nanoparticles: potential in cancer immunotherapy

F Maiyo, M Singh - Pharmaceuticals, 2019 - mdpi.com
Systemic messenger RNA (mRNA) delivery, although still in its infancy, holds immense
potential for application in cancer vaccination and immunotherapy. Its advantages over DNA …