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Microbial biofilm: a review on formation, infection, antibiotic resistance, control measures, and innovative treatment
S Sharma, J Mohler, SD Mahajan, SA Schwartz… - Microorganisms, 2023 - mdpi.com
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …
matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to …
The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
antibiotics are becoming less effective against these bacteria, such that we risk entering a …
Antibiotic resistance and persistence—Implications for human health and treatment perspectives
Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …
treatment failure and relapsing infections. They are thus important drivers of increased …
Biofilms: Formation, drug resistance and alternatives to conventional approaches
R Mirghani, T Saba, H Khaliq, J Mitchell… - AIMS …, 2022 - pmc.ncbi.nlm.nih.gov
Biofilms are aggregates of bacteria, in most cases, which are resistant usually to broad-
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …
spectrum antibiotics in their typical concentrations or even in higher doses. A trend of …
Biofilm dispersion
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …
Antibiotics versus biofilm: an emerging battleground in microbial communities
D Sharma, L Misba, AU Khan - Antimicrobial Resistance & Infection …, 2019 - Springer
Biofilm is a complex structure of microbiome having different bacterial colonies or single type
of cells in a group; adhere to the surface. These cells are embedded in extracellular …
of cells in a group; adhere to the surface. These cells are embedded in extracellular …
Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models
I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …
Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria
CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …
Persistent bacterial infections and persister cells
RA Fisher, B Gollan, S Helaine - Nature Reviews Microbiology, 2017 - nature.com
Many bacteria can infect and persist inside their hosts for long periods of time. This can be
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …
due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective …
Biofilm and wound healing: From bench to bedside
The bubbling community of microorganisms, consisting of diverse colonies encased in a self-
produced protective matrix and playing an essential role in the persistence of infection and …
produced protective matrix and playing an essential role in the persistence of infection and …