Recent advances in understanding enteric pathogenic Escherichia coli
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …
Infection strategies of enteric pathogenic Escherichia coli
Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
ARC Wong, JS Pearson, MD Bright… - Molecular …, 2011 - Wiley Online Library
The human pathogens enteropathogenic and enterohemorrhagic Escherichia coli (EPEC
and EHEC) share a unique mechanism of colonization that results from the concerted action …
and EHEC) share a unique mechanism of colonization that results from the concerted action …
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc
The L-type amino acid transporter 1 (LAT1 or SLC7A5) transports large neutral amino acids
across the membrane and is crucial for brain drug delivery and tumor growth. LAT1 forms a …
across the membrane and is crucial for brain drug delivery and tumor growth. LAT1 forms a …
Type III secretion system effectors form robust and flexible intracellular virulence networks
Infections with many Gram-negative pathogens, including Escherichia coli, Salmonella,
Shigella, and Yersinia, rely on type III secretion system (T3SS) effectors. We hypothesized …
Shigella, and Yersinia, rely on type III secretion system (T3SS) effectors. We hypothesized …
Metalloprotease type III effectors that specifically cleave JNK and NF‐κB
K Baruch, L Gur‐Arie, C Nadler, S Koby… - The EMBO …, 2011 - embopress.org
Two major arms of the inflammatory response are the NF‐κB and c‐Jun N‐terminal kinase
(JNK) pathways. Here, we show that enteropathogenic Escherichia coli (EPEC) employs the …
(JNK) pathways. Here, we show that enteropathogenic Escherichia coli (EPEC) employs the …
The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli
Background Escherichia coli is a model prokaryote, an important pathogen, and a key
organism for industrial biotechnology. E. coli W (ATCC 9637), one of four strains designated …
organism for industrial biotechnology. E. coli W (ATCC 9637), one of four strains designated …
LEEways: tales of EPEC, ATEC and EHEC
MA Schmidt - Cellular microbiology, 2010 - Wiley Online Library
Intestinal pathogenic Escherichia coli are a major cause of worldwide morbidity and
mortality. Currently seven intestinal pathovars are recognized causing a wide range of …
mortality. Currently seven intestinal pathovars are recognized causing a wide range of …
The Locus of Enterocyte Effacement and Associated Virulence Factors of Enterohemorrhagic Escherichia coli
MP Stevens, GM Frankel - … and Other Shiga Toxin‐Producing E …, 2015 - Wiley Online Library
Enterohemorrhagic Escherichia coli (EHEC) was first recognized as a cause of human
disease in 1983 and is associated with diarrhea and hemorrhagic colitis, which may be …
disease in 1983 and is associated with diarrhea and hemorrhagic colitis, which may be …
A type III effector protease NleC from enteropathogenic Escherichia coli targets NF‐κB for degradation
JS Pearson, P Riedmaier, O Marchès… - Molecular …, 2011 - Wiley Online Library
Many bacterial pathogens utilize a type III secretion system (T3SS) to inject virulence effector
proteins into host cells during infection. Previously, we found that enteropathogenic …
proteins into host cells during infection. Previously, we found that enteropathogenic …