Recent advances in understanding enteric pathogenic Escherichia coli

MA Croxen, RJ Law, R Scholz… - Clinical microbiology …, 2013 - journals.asm.org
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

Infection strategies of enteric pathogenic Escherichia coli

A Clements, JC Young, N Constantinou, G Frankel - Gut microbes, 2012 - Taylor & Francis
Enteric Escherichia coli (E. coli) are both natural flora of humans and important pathogens
causing significant morbidity and mortality worldwide. Traditionally enteric E. coli have been …

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

Y Lee, P Wiriyasermkul, C **, L Quan… - Nature structural & …, 2019 - nature.com
The L-type amino acid transporter 1 (LAT1 or SLC7A5) transports large neutral amino acids
across the membrane and is crucial for brain drug delivery and tumor growth. LAT1 forms a …

Type III secretion system effectors form robust and flexible intracellular virulence networks

D Ruano-Gallego, J Sanchez-Garrido, Z Kozik… - Science, 2021 - science.org
Infections with many Gram-negative pathogens, including Escherichia coli, Salmonella,
Shigella, and Yersinia, rely on type III secretion system (T3SS) effectors. We hypothesized …

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

ARC Wong, JS Pearson, MD Bright… - Molecular …, 2011 - Wiley Online Library
The human pathogens enteropathogenic and enterohemorrhagic Escherichia coli (EPEC
and EHEC) share a unique mechanism of colonization that results from the concerted action …

Metalloprotease type III effectors that specifically cleave JNK and NF‐κB

K Baruch, L Gur‐Arie, C Nadler, S Koby… - The EMBO …, 2011 - embopress.org
Two major arms of the inflammatory response are the NF‐κB and c‐Jun N‐terminal kinase
(JNK) pathways. Here, we show that enteropathogenic Escherichia coli (EPEC) employs the …

The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli

CT Archer, JF Kim, H Jeong, JH Park, CE Vickers… - BMC genomics, 2011 - Springer
Background Escherichia coli is a model prokaryote, an important pathogen, and a key
organism for industrial biotechnology. E. coli W (ATCC 9637), one of four strains designated …

LEEways: tales of EPEC, ATEC and EHEC

MA Schmidt - Cellular microbiology, 2010 - Wiley Online Library
Intestinal pathogenic Escherichia coli are a major cause of worldwide morbidity and
mortality. Currently seven intestinal pathovars are recognized causing a wide range of …

Bacteria–organelle communication in physiology and disease

YT Lee, M Senturk, Y Guan, MC Wang - Journal of Cell Biology, 2024 - rupress.org
Bacteria, omnipresent in our environment and coexisting within our body, exert dual
beneficial and pathogenic influences. These microorganisms engage in intricate interactions …

The Locus of Enterocyte Effacement and Associated Virulence Factors of Enterohemorrhagic Escherichia coli

MP Stevens, GM Frankel - … and Other Shiga Toxin‐Producing E …, 2015 - Wiley Online Library
Enterohemorrhagic Escherichia coli (EHEC) was first recognized as a cause of human
disease in 1983 and is associated with diarrhea and hemorrhagic colitis, which may be …