FDA-approved bone grafts and bone graft substitute devices in bone regeneration

CE Gillman, AC Jayasuriya - Materials Science and Engineering: C, 2021 - Elsevier
To induce bone regeneration there is a complex cascade of growth factors. Growth factors
such as recombinant BMP-2, BMP-7, and PDGF are FDA-approved therapies in bone …

Calcium phosphate cements for bone engineering and their biological properties

HHK Xu, P Wang, L Wang, C Bao, Q Chen, MD Weir… - Bone research, 2017 - nature.com
Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their
discovery in the 1980s, extensive research has been conducted to improve their properties …

Review of bone graft and bone substitutes with an emphasis on fracture surgeries

HS Sohn, JK Oh - Biomaterials research, 2019 - spj.science.org
Background Autogenous bone graft is the gold standard bone graft material. However, due
to limitations of supply and morbidity associated with autograft harvest, various bone …

Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties

J Zhang, W Liu, V Schnitzler, F Tancret, JM Bouler - Acta biomaterialia, 2014 - Elsevier
Since their initial formulation in the 1980s, calcium phosphate cements (CPCs) have been
increasingly used as bone substitutes. This article provides an overview on the chemistry …

Nanoscale hydroxyapatite particles for bone tissue engineering

H Zhou, J Lee - Acta biomaterialia, 2011 - Elsevier
Hydroxyapatite (HAp) exhibits excellent biocompatibility with soft tissues such as skin,
muscle and gums, making it an ideal candidate for orthopedic and dental implants or …

[HTML][HTML] Calcium orthophosphates in nature, biology and medicine

SV Dorozhkin - Materials, 2009 - mdpi.com
The present overview is intended to point the readers' attention to the important subject of
calcium orthophosphates. These materials are of the special significance because they …

Minimally invasive and regenerative therapeutics

N Ashammakhi, S Ahadian, MA Darabi… - Advanced …, 2019 - Wiley Online Library
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …

Calcium orthophosphates

SV Dorozhkin - Journal of materials science, 2007 - Springer
The present overview is intended to point the readers' attention to the important subject of
calcium orthophosphates. This type of materials is of the special significance for the human …

Ceramic composites as matrices and scaffolds for drug delivery in tissue engineering

W Habraken, JGC Wolke, JA Jansen - Advanced drug delivery reviews, 2007 - Elsevier
Ceramic composites and scaffolds are popular implant materials in the field of dentistry,
orthopedics and plastic surgery. For bone tissue engineering especially CaP-ceramics or …

[HTML][HTML] Biological and mechanical performance and degradation characteristics of calcium phosphate cements in large animals and humans

L Schröter, F Kaiser, S Stein, U Gbureck, A Ignatius - Acta biomaterialia, 2020 - Elsevier
Calcium phosphate cements (CPCs) have been used to treat bone defects and support
bone regeneration because of their good biocompatibility and osteointegrative behavior …