Computational modeling of realistic cell membranes
Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …
Emerging diversity in lipid–protein interactions
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …
membrane environment for proteins to being embedded in to detailed roles in complicated …
Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Receptor tyrosine kinase activation: From the ligand perspective
Receptor tyrosine kinases (RTKs) are single-span transmembrane receptors in which
relatively conserved intracellular kinase domains are coupled to divergent extracellular …
relatively conserved intracellular kinase domains are coupled to divergent extracellular …
Activation of the EGF receptor by ligand binding and oncogenic mutations: the “rotation model”
ER Purba, E Saita, IN Maruyama - Cells, 2017 - mdpi.com
The epidermal growth factor receptor (EGFR) plays vital roles in cellular processes including
cell proliferation, survival, motility, and differentiation. The dysregulated activation of the …
cell proliferation, survival, motility, and differentiation. The dysregulated activation of the …
The RTK interactome: overview and perspective on RTK heterointeractions
Receptor tyrosine kinases (RTKs) play important roles in cell growth, motility, differentiation,
and survival. These single-pass membrane proteins are grouped into subfamilies based on …
and survival. These single-pass membrane proteins are grouped into subfamilies based on …
Eukaryotic cell membranes: structure, composition, research methods and computational modelling
A Zhukov, V Popov - International Journal of Molecular Sciences, 2023 - mdpi.com
This paper deals with the problems encountered in the study of eukaryotic cell membranes.
A discussion on the structure and composition of membranes, lateral heterogeneity of …
A discussion on the structure and composition of membranes, lateral heterogeneity of …
Membrane receptor activation mechanisms and transmembrane peptide tools to elucidate them
Single-pass membrane receptors contain extracellular domains that respond to external
stimuli and transmit information to intracellular domains through a single transmembrane …
stimuli and transmit information to intracellular domains through a single transmembrane …
It takes more than two to tango: Complex, hierarchal, and membrane-modulated interactions in the regulation of receptor tyrosine kinases
Simple Summary Receptor tyrosine kinases probably constitute the most important
subfamily of transmembrane receptors with respect to their role in regulating the balance …
subfamily of transmembrane receptors with respect to their role in regulating the balance …
Structural studies providing insights into production and conformational behavior of amyloid-β peptide associated with Alzheimer's disease development
AS Urban, KV Pavlov, AV Kamynina, IS Okhrimenko… - Molecules, 2021 - mdpi.com
Alzheimer's disease is the most common type of neurodegenerative disease in the world.
Genetic evidence strongly suggests that aberrant generation, aggregation, and/or clearance …
Genetic evidence strongly suggests that aberrant generation, aggregation, and/or clearance …