Curcuma longa (C. longa) or turmeric is a plant with a long history of use in traditional
medicine, especially for treating inflammatory conditions C. longa and its main constituent …

Phytochemicals are known to have anti-inflammatory effects in vitro and in vivo, such as in
inflammatory disease model systems. Inflammation is an essential immune response to …

Background: Alzheimer's disease (AD) is increasingly prevalent and over 99% of drugs
developed for AD have failed in clinical trials. A growing body of literature suggests that …

Curcumin is a polyphenol compound extracted from the rhizome of Curcuma longa Linn
(family Zingiberaceae) commonly used as a spice to color and flavor food. Several …

Oxidative damage, mitochondrial dysfunction, and neuroinflammation are strongly
implicated in the pathogenesis of neurodegenerative diseases including Alzheimer's …

Age-related hearing loss (ARHL) is a most widespread neurodegenerative disease affecting
the elderly population, but effective pharmacological treatments remain limited. Curcumin is …

Background: Pathological pain conditions can be triggered after peripheral nerve injury
and/or inflammation. It is a major clinical problem that is poorly treated with available …

Background: Migraine is a common neuroinflammatory disorder characterized by recurrent
attacks of pain. Human and experimental models of migraine studies have demonstrated the …

Activation of the proinflammatory‐associated cytokine, tumor necrosis factor-α (TNF-α), in
nucleus pulposus (NP) cells is essential for the pathogenesis of intervertebral disc …

It has been extensively verified that inflammation and oxidative stress play important roles in
the pathogenesis of cardiovascular diseases (CVDs). Curcuminoids, from the plant Curcuma …