Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

Angiogenesis and wound repair: when enough is enough

LA DiPietro - Journal of Leucocyte Biology, 2016 - academic.oup.com
All animals heal, and the ability to heal is requisite for human health. One aspect of repair
that has always been considered to be essential for adequate healing is the creation of a …

[HTML][HTML] Oral wound healing models and emerging regenerative therapies

AI Toma, JM Fuller, NJ Willett, SL Goudy - Translational Research, 2021 - Elsevier
Following injury, the oral mucosa undergoes complex sequences of biological healing
processes to restore homeostasis. While general similarities exist, there are marked …

Periodontal wound healing and tissue regeneration: a narrative review

YD Cho, KH Kim, YM Lee, Y Ku, YJ Seol - Pharmaceuticals, 2021 - mdpi.com
Periodontal disease is a major public health issue, and various periodontal therapies have
been performed to regenerate periodontal tissues. The periodontium is a complex structure …

[HTML][HTML] Toward understanding scarless skin wound healing and pathological scarring

SM Karppinen, R Heljasvaara, D Gullberg… - …, 2019 - ncbi.nlm.nih.gov
The efficient healing of skin wounds is crucial for securing the vital barrier function of the
skin, but pathological wound healing and scar formation are major medical problems …

The bigger picture: Why oral mucosa heals better than skin

M Waasdorp, BP Krom, FJ Bikker, PPM van Zuijlen… - Biomolecules, 2021 - mdpi.com
Wound healing is an essential process to restore tissue integrity after trauma. Large skin
wounds such as burns often heal with hypertrophic scarring and contractures, resulting in …

Transcriptional signature primes human oral mucosa for rapid wound healing

R Iglesias-Bartolome, A Uchiyama… - Science translational …, 2018 - science.org
Oral mucosal wound healing has long been regarded as an ideal system of wound
resolution. However, the intrinsic characteristics that mediate optimal healing at mucosal …

Accelerated burn wound healing with photobiomodulation therapy involves activation of endogenous latent TGF-β1

I Khan, SU Rahman, E Tang, K Engel, B Hall… - Scientific reports, 2021 - nature.com
The severity of tissue injury in burn wounds from associated inflammatory and immune
sequelae presents a significant clinical management challenge. Among various biophysical …

Macrophages in healing wounds: paradoxes and paradigms

LA DiPietro, TA Wilgus, TJ Koh - International journal of molecular …, 2021 - mdpi.com
Macrophages are prominent cells in normally healing adult skin wounds, yet their exact
functions and functional significance to healing outcomes remain enigmatic. Many functional …

Junctional epithelium and hemidesmosomes: Tape and rivets for solving the “percutaneous device dilemma” in dental and other permanent implants

NG Fischer, C Aparicio - Bioactive materials, 2022 - Elsevier
The percutaneous device dilemma describes etiological factors, centered around the
disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant …