During the last few decades, improvements in the planning and application of radiotherapy
in combination with surgery and chemotherapy resulted in increased survival rates of tumor …

The main goal when treating malignancies with radiation therapy is to deprive tumor cells of
their reproductive potential. One approach to achieve this is by inducing tumor cell …

Cancer is the principal cause of death and its incidence is increasing continuously
worldwide. Various treatment approaches are in practice to treat cancer, but these treatment …

The strategy of clinically targeting cancerous cells at their most vulnerable state during
mitosis has instigated numerous studies into the mitotic cell death (MCD) pathway. As the …

Leukemia is a life-threatening nonepithelial malignant disorder that is characterized by
uncontrolled growth of the hematopoietic cells. To date, there are still unmet needs for …

Background This study explores and characterizes cell cycle alterations induced by urban
PM2. 5 in the human epithelial cell line BEAS-2B, and elucidates possible mechanisms …

Inhibition of PCAF bromodomain has been validated as a promising strategy for the
treatment of cancer. In this study, we report the bioisosteric modification of the first reported …

Natural compounds from various plants, microorganisms and marine species play an
important role in the discovery novel components that can be successfully used in numerous …

Cellular growth and the preparation of cells for division between two successive cell
divisions is called the cell cycle. The cell cycle is divided into several phases; the length of …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …