Edible mushrooms as potential functional foods in amelioration of hypertension

A Rauf, PB Joshi, Z Ahmad, HA Hemeg… - Phytotherapy …, 2023‏ - Wiley Online Library
Edible mushrooms are popular functional foods attributed to their rich nutritional bioactive
constituent profile influencing cardiovascular function. Edible mushrooms are omnipresent …

Architecture design and advanced manufacturing of heart-on-a-chip: scaffolds, stimulation and sensors

F Xu, H **, L Liu, Y Yang, J Cen, Y Wu… - Microsystems & …, 2024‏ - nature.com
Abstract Heart-on-a-chip (HoC) has emerged as a highly efficient, cost-effective device for
the development of engineered cardiac tissue, facilitating high-throughput testing in drug …

Imaging cellular forces with photonic crystals

Q Li, Z Chen, Y Zhang, S Ding, H Ding, L Wang… - Nature …, 2023‏ - nature.com
Current techniques for visualizing and quantifying cellular forces have limitations in live cell
imaging, throughput, and multi-scale analysis, which impede progress in cell force research …

Integrated technologies for continuous monitoring of organs-on-chips: Current challenges and potential solutions

JS Del Rio, J Ro, H Yoon, TE Park, YK Cho - Biosensors and Bioelectronics, 2023‏ - Elsevier
Abstract Organs-on-chips (OoCs) are biomimetic in vitro systems based on microfluidic cell
cultures that recapitulate the in vivo physicochemical microenvironments and the …

Ultrathin and flexible bioelectronic arrays for functional measurement of iPSC-cardiomyocytes under cardiotropic drug administration and controlled …

W Dou, A Daoud, X Chen, T Wang, M Malhi, Z Gong… - Nano Letters, 2023‏ - ACS Publications
Emerging heart-on-a-chip technology is a promising tool to establish in vitro cardiac models
for therapeutic testing and disease modeling. However, due to the technical complexity of …

Revisiting cardiac biology in the era of single cell and spatial omics

JA Palmer, N Rosenthal, SA Teichmann… - Circulation …, 2024‏ - ahajournals.org
Throughout our lifetime, each beat of the heart requires the coordinated action of multiple
cardiac cell types. Understanding cardiac cell biology, its intricate microenvironments, and …

Biohybrid printing approaches for cardiac pathophysiological studies

DG Hwang, W Kang, SM Park, J Jang - Biosensors and Bioelectronics, 2024‏ - Elsevier
Bioengineered hearts, which include single cardiomyocytes, engineered heart tissue, and
chamber-like models, generate various biosignals, such as contractility …

A carbon-based biosensing platform for simultaneously measuring the contraction and electrophysiology of iPSC-cardiomyocyte monolayers

W Dou, M Malhi, T Cui, M Wang, T Wang, G Shan… - ACS …, 2022‏ - ACS Publications
Heart beating is triggered by the generation and propagation of action potentials through the
myocardium, resulting in the synchronous contraction of cardiomyocytes. This process …

Interferometric Biosensor for High Sensitive Label-Free Recording of HiPS Cardiomyocytes Contraction in Vitro

A Boschi, G Iachetta, S Buonocore, A Hubarevich… - Nano Letters, 2024‏ - ACS Publications
Heart disease remains a leading cause of global mortality, underscoring the need for
advanced technologies to study cardiovascular diseases and develop effective treatments …

[HTML][HTML] Heart-on-a-chip systems with tissue-specific functionalities for physiological, pathological, and pharmacological studies

B Gu, K Han, H Cao, X Huang, X Li, M Mao, H Zhu… - Materials Today Bio, 2024‏ - Elsevier
Recent advances in heart-on-a-chip systems hold great promise to facilitate cardiac
physiological, pathological, and pharmacological studies. This review focuses on the …