Microneedles for painless transdermal immunotherapeutic applications

H Amani, MA Shahbazi, C D'Amico, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …

Device-assisted transdermal drug delivery

H Lee, C Song, S Baik, D Kim, T Hyeon… - Advanced drug delivery …, 2018 - Elsevier
Transdermal drug delivery is a prospective drug delivery strategy to complement the
limitations of conventional drug delivery systems including oral and injectable methods. This …

[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication

LE Moore, S Vucen, AC Moore - European Journal of Pharmaceutics and …, 2022 - Elsevier
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …

Dissolving microneedle patches for dermal vaccination

M Leone, J Mönkäre, JA Bouwstra, G Kersten - Pharmaceutical research, 2017 - Springer
The dermal route is an attractive route for vaccine delivery due to the easy skin accessibility
and a dense network of immune cells in the skin. The development of microneedles is …

Antimalarial drug discovery against malaria parasites through haplopine modification: an advanced computational approach

S Akash, G Abdelkrim, I Bayil, ME Hosen… - Journal of Cellular …, 2023 - Wiley Online Library
The widespread emergence of antimalarial drug resistance has created a major threat to
public health. Malaria is a life‐threatening infectious disease caused by Plasmodium spp …

Microneedle patches as drug and vaccine delivery platform

J Li, M Zeng, H Shan, C Tong - Current medicinal chemistry, 2017 - ingentaconnect.com
Background: Transcutaneous delivery is the ideal method for delivering therapeutic
reagents or vaccines into skin. With their promise of self-administration, cost-effective and …

Microneedle patches for vaccination in develo** countries

J Arya, MR Prausnitz - Journal of Controlled Release, 2016 - Elsevier
Millions of people die of infectious diseases each year, mostly in develo** countries,
which could largely be prevented by the use of vaccines. While immunization rates have …

[HTML][HTML] Hollow silicon microneedles, fabricated using combined wet and dry etching techniques, for transdermal delivery and diagnostics

C O'Mahony, R Sebastian, F Tjulkins, D Whelan… - International Journal of …, 2023 - Elsevier
Microneedle-based technologies are the subject of intense research and commercial
interest for applications in transdermal delivery and diagnostics, primarily because of their …

The role of microneedles for drug and vaccine delivery

HL Quinn, MC Kearney, AJ Courtenay… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Transdermal drug delivery offers a number of advantages for the patient, not
only due to its non-invasive and convenient nature, but also due to factors such as …

Production of dissolvable microneedles using an atomised spray process: Effect of microneedle composition on skin penetration

MG McGrath, S Vucen, A Vrdoljak, A Kelly… - European journal of …, 2014 - Elsevier
Dissolvable microneedles offer an attractive delivery system for transdermal drug and
vaccine delivery. They are most commonly formed by filling a microneedle mold with liquid …