The origin and fate of chondrocytes: cell plasticity in physiological setting

AS Chagin, TL Chu - Current Osteoporosis Reports, 2023 - Springer
Abstract Purpose of Review Here, we discuss the origin of chondrocytes, their destiny, and
their plasticity in relationship to bone growth, articulation, and formation of the trabeculae …

Functional adaptive landscapes predict terrestrial capacity at the origin of limbs

BV Dickson, JA Clack, TR Smithson, SE Pierce - Nature, 2021 - nature.com
The acquisition of terrestrial, limb-based locomotion during tetrapod evolution has remained
a subject of debate for more than a century,. Our current understanding of the locomotor …

An ERK-dependent feedback mechanism prevents hematopoietic stem cell exhaustion

C Baumgartner, S Toifl, M Farlik, F Halbritter… - Cell stem cell, 2018 - cell.com
Hematopoietic stem cells (HSCs) sustain hematopoiesis throughout life. HSCs exit
dormancy to restore hemostasis in response to stressful events, such as acute blood loss …

Fossilized cell structures identify an ancient origin for the teleost whole-genome duplication

D Davesne, M Friedman, AD Schmitt… - Proceedings of the …, 2021 - National Acad Sciences
Teleost fishes comprise one-half of all vertebrate species and possess a duplicated
genome. This whole-genome duplication (WGD) occurred on the teleost stem lineage in an …

Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche

FG Kapp, JR Perlin, EJ Hagedorn, JM Gansner… - Nature, 2018 - nature.com
Haematopoietic stem and progenitor cells (HSPCs) require a specific microenvironment, the
haematopoietic niche, which regulates HSPC behaviour,. The location of this niche varies …

The origin of novel features by changes in developmental mechanisms: ontogeny and three‐dimensional microanatomy of polyodontode scales of two early …

Q Qu, S Sanchez, M Zhu, H Blom… - Biological …, 2017 - Wiley Online Library
Recent advances in synchrotron imaging allow us to study the three‐dimensional (3D)
histology of vertebrate fossils, including microfossils (eg teeth and scales) of early jawed …

Life history of the stem tetrapod Acanthostega revealed by synchrotron microtomography

S Sanchez, P Tafforeau, JA Clack, PE Ahlberg - Nature, 2016 - nature.com
The transition from fish to tetrapod was arguably the most radical series of adaptive shifts in
vertebrate evolutionary history. Data are accumulating rapidly for most aspects of these …

Palaeobiology of red and white blood cell-like structures, collagen and cholesterol in an ichthyosaur bone

C Plet, K Grice, A Pagès, M Verrall, MJL Coolen… - Scientific Reports, 2017 - nature.com
Carbonate concretions are known to contain well-preserved fossils and soft tissues.
Recently, biomolecules (eg cholesterol) and molecular fossils (biomarkers) were also …

Fossil bone histology reveals ancient origins for rapid juvenile growth in tetrapods

MR Whitney, BKA Otoo, KD Angielczyk… - Communications …, 2022 - nature.com
Patterns of growth throughout the lifetime of an animal reflect critical life history traits such as
reproductive timing, physiology, and ecological interactions. The ancestral growth pattern for …

Secondary ossification center induces and protects growth plate structure

M **e, P Gol'Din, AN Herdina, J Estefa, EV Medvedeva… - Elife, 2020 - elifesciences.org
Growth plate and articular cartilage constitute a single anatomical entity early in
development but later separate into two distinct structures by the secondary ossification …