Amino acids evolve at different speeds within protein sequences, because their functional
and structural roles are different. Notably, amino acids located at the surface of proteins are …

Abstract Growth hormone (GH), prolactin (PRL), prolactin 2 (PRL2) and somatolactin (SL)
belong to the same hormone family and have a wide repertoire of effects including …

Background Recent advances in sequencing technologies have led to an explosion in the
number of genomes available, but accurate genome annotation remains a major challenge …

The peptidyl transferase center (PTC) is the catalytic center of the ribosome and forms part of
the 23S ribosomal RNA. The PTC has been recognized as the earliest ribosomal part and its …

The receptors for the pituitary hormones growth hormone (GH), prolactin (PRL) and
somatolactin (SL), and the hematopoietic hormones erythropoietin (EPO) and …

The availability of completed and draft genome assemblies of tiger, leopard, and other felids
provides an opportunity to gain comparative insights on their unique evolutionary …

Ice-binding proteins (IBPs) have evolved independently in multiple taxonomic groups to
improve their survival at sub-zero temperatures. Intertidal invertebrates in temperate and …

In fungi, the most abundant transcription factor (TF) class contains a fungal-specific 'GAL4-
like'Zn2C6 DNA binding domain (DBD), while the second class contains another fungal …

Insertions and deletions (indels) in protein-coding genes are important sources of genetic
variation. Their role in creating new proteins may be especially important after gene …

Genome assemblies from next-generation sequencing technologies are now an integral part
of biological research, but many sequencing and assembly processes are still error-prone …