Tissue stiffness dictates development, homeostasis, and disease progression
Tissue development is orchestrated by the coordinated activities of both chemical and
physical regulators. While much attention has been given to the role that chemical regulators …
physical regulators. While much attention has been given to the role that chemical regulators …
Mechanical control of tissue and organ development
Many genes and molecules that drive tissue patterning during organogenesis and tissue
regeneration have been discovered. Yet, we still lack a full understanding of how these …
regeneration have been discovered. Yet, we still lack a full understanding of how these …
Mechanobiology and developmental control
T Mammoto, A Mammoto… - Annual review of cell and …, 2013 - annualreviews.org
Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …
and organs that exhibit specialized form and function during embryological development …
Muscular thin films for building actuators and powering devices
We demonstrate the assembly of biohybrid materials from engineered tissues and synthetic
polymer thin films. The constructs were built by culturing neonatal rat ventricular …
polymer thin films. The constructs were built by culturing neonatal rat ventricular …
Left ventricular structure and function: basic science for cardiac imaging
PP Sengupta, J Korinek, M Belohlavek, J Narula… - Journal of the American …, 2006 - jacc.org
The myofiber geometry of the left ventricle (LV) changes gradually from a right-handed helix
in the subendocardium to a left-handed helix in the subepicardium. In this review, we …
in the subendocardium to a left-handed helix in the subepicardium. In this review, we …
Perspective: The promise of multi-cellular engineered living systems
Recent technological breakthroughs in our ability to derive and differentiate induced
pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all …
pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all …
Transgenic fluorescent zebrafish lines that have revolutionized biomedical research
CP Choe, SY Choi, Y Kee, MJ Kim, SH Kim… - Laboratory Animal …, 2021 - Springer
Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …
vertebrate model organism in more than 40,000 biomedical research studies. Especially …
Uncovering the molecular and cellular mechanisms of heart development using the zebrafish
Over the past 20 years, the zebrafish has emerged as a powerful model organism for
studying cardiac development. Its ability to survive without an active circulation and …
studying cardiac development. Its ability to survive without an active circulation and …
Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Develo** Heart
Heart valve anomalies are some of the most common congenital heart defects, yet neither
the genetic nor the epigenetic forces guiding heart valve development are well understood …
the genetic nor the epigenetic forces guiding heart valve development are well understood …
Zebrafish and Medaka: new model organisms for modern biomedical research
CY Lin, CY Chiang, HJ Tsai - Journal of biomedical science, 2016 - Springer
Although they are primitive vertebrates, zebrafish (Danio rerio) and medaka (Oryzias latipes)
have surpassed other animals as the most used model organisms based on their many …
have surpassed other animals as the most used model organisms based on their many …