The arboviruses that cause dengue, chikungunya, and Zika illnesses have rapidly expanded
across the globe in recent years, with large-scale outbreaks occurring in Western …

The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

Dengue fever is considered the most prolific vector-borne disease in the world, with its
transmission rate increasing more than eight times in the last two decades. While most …

Dengue is widespread throughout the tropics and local spatial variation in dengue virus
transmission is strongly influenced by rainfall, temperature, urbanization and distribution of …

Background Over the last 30 years, extensive dengue epidemics have occurred in Brazil,
characterized by emergences and re-emergences of different serotypes, a change in the …

Background The control groups in two phase 3 trials of dengue vaccine efficacy included
two large regional cohorts that were followed up for dengue infection. These cohorts …

ABSTRACT The World Health Organization (WHO) introduced the new dengue classification
in 2009. We aimed to assess the association of clinical signs and symptoms with WHO …

Background: Dengue virus is a flavivirus transmitted by Aedes mosquitoes and is an
important cause of illness worldwide. Data on the severity of travel-associated dengue …

There is no specific treatment of dengue, and a changing climate, insecticide resistance and
urban expansion have permitted the vector's spread, making the vector control almost …

This review describes and commentates on recent advances in the understanding of
dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics …