Fluorine in the pharmaceutical industry: Synthetic approaches and application of clinically approved fluorine-enriched anti-infectious medications

ZX Niu, J Hu, JF Sun, YT Wang - European Journal of Medicinal Chemistry, 2024 - Elsevier
The strategic integration of fluorine atoms into anti-infectious agents has become a
cornerstone in the field of medicinal chemistry, owing to the unique influence of fluorine on …

[HTML][HTML] Trofinetide for Rett syndrome: highlights on the development and related inventions of the first USFDA-approved treatment for rare pediatric unmet medical …

SA Hudu, F Elmigdadi, AA Qtaitat… - Journal of Clinical …, 2023 - mdpi.com
Rett syndrome (RTT) is a rare disability causing female-oriented pediatric
neurodevelopmental unmet medical need. RTT was recognized in 1966. However, over the …

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

MA Shamim, P Satapathy, BK Padhi… - Frontiers in …, 2023 - frontiersin.org
Mpox (earlier known as monkeypox) virus infection is a recognized public health
emergency. There has been little research on the treatment options. This article reviews the …

The prospective outcome of the monkeypox outbreak in 2022 and characterization of monkeypox disease immunobiology

MS Qudus, X Cui, M Tian, U Afaq, M Sajid… - Frontiers in Cellular …, 2023 - frontiersin.org
A new threat to global health re-emerged with monkeypox's advent in early 2022. As of
November 10, 2022, nearly 80,000 confirmed cases had been reported worldwide, with …

The global patent landscape of emerging infectious disease monkeypox

Y Cai, X Zhang, K Zhang, J Liang, P Wang… - BMC Infectious …, 2024 - Springer
Background Monkeypox is an emerging infectious disease with confirmed cases and deaths
in several parts of the world. In light of this crisis, this study aims to analyze the global …

The 2022 monkeypox outbreak 1 year on: The 5 Ws

G Khan, N Perveen - Reviews in Medical Virology, 2024 - Wiley Online Library
Abstract In May 2022, World Health Organization (WHO) reported an outbreak of Mpox in
several European countries which were previously Mpox free. Mpox (formerly known as …

[HTML][HTML] Therapeutic strategies for human poxvirus infections: Monkeypox (mpox), smallpox, molluscipox, and orf

E De Clercq, Y Jiang, G Li - Travel Medicine and Infectious Disease, 2023 - Elsevier
Therapeutic and vaccine development for human poxvirus infections (eg, monkeypox
(mpox) virus, variola virus, molluscum contagiosum virus, orf virus) has been largely …

A fractional mathematical model for vaccinated humans with the impairment of Monkeypox transmission

A Venkatesh, M Manivel, K Arunkumar… - The European Physical …, 2024 - Springer
This research develops a comprehensive numerical model leveraging fuzzy fractional
differential equations to analyze the transmission dynamics of the Monkeypox virus. Using …