Aptamers with high affinity and specificity for certain targets have rapidly become a novel
class of targeted ligands applicated in drug delivery. Based on the excellent characteristics …

DNA materials have emerged as potential nanocarriers for targeted cancer therapy to
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …

Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …

Functionally modified aptamer conjugates are promising tools for targeted imaging or
treatment of various diseases. However, broad applications of aptamer molecules are …

Pancreatic cancer is one of the most malignant tumors with the highest mortality rates, and it
currently lacks effective drugs. Aptamer-drug conjugates (ApDC), as a form of nucleic acid …

Drug conjugates are obtained from tumor-located vectors connected to cytotoxic agents via
linkers, which are designed to deliver hyper-toxic payloads directly to targeted cancer cells …

Here, we report photoinitiated polymerization-induced self-assembly (photo-PISA) mediated
by Rose Bengal methacrylate (RBMA) to reproducibly construct nanoparticles in one pot, on …

Natural compounds like pterostilbene (PTE) have gained recognition for their various
biological activities and potential health benefits. However, challenges related to …

Aptamers are short single-strand oligonucleotides that can form secondary and tertiary
structures, fitting targets with high affinity and specificity. They are so-called “chemical …

Safely and effectively harnessing innate immunity to boost cancer immunotherapy is
promising yet challenging. Hence, we have developed a series of programmable aptamer …