Isoxazolidine: a privileged scaffold for organic and medicinal chemistry

M Berthet, T Cheviet, G Dujardin, I Parrot… - Chemical …, 2016 - ACS Publications
The isoxazolidine ring represents one of the privileged structures in medicinal chemistry,
and there have been an increasing number of studies on isoxazolidine and isoxazolidine …

Recent advances in indium-promoted organic reactions

J Auge, N Lubin-Germain, J Uziel - Synthesis, 2007 - thieme-connect.com
This review deals with organic reactions which are promoted by indium metal or indium
salts, with a focus on recent advances in stoichiometric and catalytic pathways. Applications …

Cp∗ Ir-catalyzed N-alkylation of amines with alcohols. A versatile and atom economical method for the synthesis of amines

K Fujita, Y Enoki, R Yamaguchi - Tetrahedron, 2008 - Elsevier
A versatile and highly atom economical catalytic system consisting of [Cp∗ IrCl2] 2/NaHCO3
(Cp∗= pentamethylcyclopentadienyl) for the N-alkylation of amines with primary and …

Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols

CX Ye, YY Melcamu, HH Li, JT Cheng… - Nature …, 2018 - nature.com
Enantiopure vicinal amino alcohols and derivatives are essential structural motifs in natural
products and pharmaceutically active molecules, and serve as main chiral sources in …

Metal‐Free Reductive Cleavage of C N and S N Bonds by Photoactivated Electron Transfer from a Neutral Organic Donor

S O'Sullivan, E Doni, T Tuttle… - Angewandte Chemie …, 2014 - Wiley Online Library
A photoactivated neutral organic super electron donor cleaves challenging
arenesulfonamides derived from dialkylamines at room temperature. It also cleaves a) ArC …

Harnessing phosphonate antibiotics argolaphos biosynthesis enables a synthetic biology-based green synthesis of glyphosate

L Chu, X Luo, T Zhu, Y Cao, L Zhang, Z Deng… - Nature …, 2022 - nature.com
Glyphosate is a widely used herbicide with an annual production of more than one million
tons globally. Current commercialized production processes of glyphosate are generally …

Radical cation and neutral radical of aza-thia [7] helicene with SOMO–HOMO energy level inversion

Y Wang, H Zhang, M Pink, A Olankitwanit… - Journal of the …, 2016 - ACS Publications
We report a relatively persistent, open-shell aza-thia [7] helicene with cross-conjugated
electron-rich π-system. The singly occupied molecular orbital (SOMO) energy levels of both …

Total synthesis of (±)-haouamine A

PS Baran, NZ Burns - Journal of the American Chemical Society, 2006 - ACS Publications
The first total synthesis of the highly complex and potent anticancer agent haouamine A is
reported through an eight-step sequence. Brevity of the sequence and complete control of …

Intermolecular Cope-type hydroamination of alkenes and alkynes using hydroxylamines

J Moran, SI Gorelsky, E Dimitrijevic… - Journal of the …, 2008 - ACS Publications
The development of the Cope-type hydroamination as a method for the metal-and acid-free
intermolecular hydroamination of hydroxylamines with alkenes and alkynes is described …

Stereoselective isoxazolidine synthesis via copper-catalyzed alkene aminooxygenation

SD Karyakarte, TP Smith… - The Journal of organic …, 2012 - ACS Publications
Isoxazolidines are useful in organic synthesis, drug discovery, and chemical biology
endeavors. A new stereoselective synthesis of methyleneoxy-substituted isoxazolidines is …