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Synthesis, dynamics and applications (cytotoxicity and biocompatibility) of dendrimers: A mini-review
Dendrimers are an excellent candidate that exhibits higher proficiency in biomedical
applications such as drug delivery, inhibition and/or targeting gene delivery. The use of …
applications such as drug delivery, inhibition and/or targeting gene delivery. The use of …
[HTML][HTML] Application of new lysine-based peptide dendrimers D3K2 and D3G2 for gene delivery: Specific cytotoxicity to cancer cells and transfection in vitro
M Gorzkiewicz, M Konopka, A Janaszewska… - Bioorganic …, 2020 - Elsevier
In order to enhance intracellular uptake and accumulation of therapeutic nucleic acids for
improved gene therapy methods, numerous delivery vectors have been elaborated. Based …
improved gene therapy methods, numerous delivery vectors have been elaborated. Based …
NMR relaxation in dendrimers
DA Markelov, M Dolgushev, E Lähderanta - Annual Reports on NMR …, 2017 - Elsevier
This review focuses on recent advances in the theory of local orientational mobility in
dendrimers that reveals in the NMR relaxation. In particular, we summarize recent results of …
dendrimers that reveals in the NMR relaxation. In particular, we summarize recent results of …
Lysine-based dendrimer with double arginine residues
NN Sheveleva, DA Markelov, MA Vovk… - RSC …, 2019 - pubs.rsc.org
Due to their well-defined structure, multivalency, biocompatibility, and low toxicity, lysine
dendrimers can be used as safe and efficient nanocarriers for drug and gene delivery. One …
dendrimers can be used as safe and efficient nanocarriers for drug and gene delivery. One …
Structure of asymmetrical peptide dendrimers: Insights given by self-consistent field theory
BM Okrugin, IM Neelov, FAM Leermakers, OV Borisov - Polymer, 2017 - Elsevier
Structural properties of asymmetric peptide dendrimers up to the 11th generation are studied
on the basis of the self-consistent field Scheutjens-Fleer numerical approach. It is …
on the basis of the self-consistent field Scheutjens-Fleer numerical approach. It is …
NMR studies of excluded volume interactions in peptide dendrimers
NN Sheveleva, DA Markelov, MA Vovk… - Scientific reports, 2018 - nature.com
Peptide dendrimers are good candidates for diverse biomedical applications due to their
biocompatibility and low toxicity. The local orientational mobility of groups with different …
biocompatibility and low toxicity. The local orientational mobility of groups with different …
[HTML][HTML] Stable deuterium labeling of histidine-rich lysine-based dendrimers
NN Sheveleva, DA Markelov, MA Vovk, II Tarasenko… - Molecules, 2019 - mdpi.com
Peptide dendrimers, due to their biocompatibility and low toxicity, are highly promising
candidates as nanocarriers for drugs and genes. The development of this kind of delivery …
candidates as nanocarriers for drugs and genes. The development of this kind of delivery …
Is the manifestation of the local dynamics in the spin–lattice NMR relaxation in dendrimers sensitive to excluded volume interactions?
OV Shavykin, IM Neelov, AA Darinskii - Physical Chemistry Chemical …, 2016 - pubs.rsc.org
The effect of excluded volume (EV) interactions on the manifestation of the local dynamics in
the spin–lattice NMR relaxation in dendrimers has been studied by using Brownian …
the spin–lattice NMR relaxation in dendrimers has been studied by using Brownian …
Self-assembly of lysine-based dendritic surfactants modeled by the self-consistent field approach
OV Shavykin, FAM Leermakers, IM Neelov… - Langmuir, 2018 - ACS Publications
Implementing a united atom model, we apply self-consistent field theory to study structure
and thermodynamic properties of spherical micelles composed of surfactants that combine …
and thermodynamic properties of spherical micelles composed of surfactants that combine …
Effect of an asymmetry of branching on structural characteristics of dendrimers revealed by Brownian dynamics simulations
OV Shavykin, IV Mikhailov, AA Darinskii, IM Neelov… - Polymer, 2018 - Elsevier
Dendrimers in dilute solution with asymmetry of branching were simulated by the Brownian
dynamics method. In this simulation a coarse-grained dendrimer model and athermal …
dynamics method. In this simulation a coarse-grained dendrimer model and athermal …