Dendritic cell migration in inflammation and immunity

J Liu, X Zhang, Y Cheng, X Cao - Cellular & molecular immunology, 2021 - nature.com
Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and
play crucial roles in both the promotion of immune defense and the maintenance of immune …

Homeostatic immunity and the microbiota

Y Belkaid, OJ Harrison - Immunity, 2017 - cell.com
The microbiota plays a fundamental role in the induction, education, and function of the host
immune system. In return, the host immune system has evolved multiple means by which to …

A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation

R Kedmi, TA Najar, KR Mesa, A Grayson, L Kroehling… - Nature, 2022 - nature.com
The mutualistic relationship of gut-resident microbiota and the host immune system
promotes homeostasis that ensures maintenance of the microbial community and of a …

Dendritic cell migration in health and disease

T Worbs, SI Hammerschmidt, R Förster - Nature Reviews Immunology, 2017 - nature.com
Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …

Food allergy: immune mechanisms, diagnosis and immunotherapy

W Yu, DMH Freeland, KC Nadeau - Nature Reviews Immunology, 2016 - nature.com
Food allergy is a pathological, potentially deadly, immune reaction triggered by normally
innocuous food protein antigens. The prevalence of food allergies is rising and the standard …

Origin, differentiation, and function of intestinal macrophages

CC Bain, A Schridde - Frontiers in immunology, 2018 - frontiersin.org
Macrophages are increasingly recognized as essential players in the maintenance of
intestinal homeostasis and as key sentinels of the intestinal immune system. However …

CD4 T-cell subsets and the pathophysiology of inflammatory bowel disease

R Gomez-Bris, A Saez, B Herrero-Fernandez… - International journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is an umbrella term for the chronic immune-mediated
idiopathic inflammation of the gastrointestinal tract, manifesting as Crohn's disease (CD) or …

[HTML][HTML] Role of the microbiota in immunity and inflammation

Y Belkaid, TW Hand - Cell, 2014 - cell.com
The microbiota plays a fundamental role on the induction, training, and function of the host
immune system. In return, the immune system has largely evolved as a means to maintain …

The chemokine system in innate immunity

CL Sokol, AD Luster - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Chemokines are chemotactic cytokines that control the migration and positioning of immune
cells in tissues and are critical for the function of the innate immune system. Chemokines …

From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity

NL Trevaskis, LM Kaminskas, CJH Porter - Nature reviews Drug …, 2015 - nature.com
The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …