Castleman disease (CD), a heterogeneous group of disorders that share morphological
features, is divided into unicentric CD and multicentric CD (MCD) according to the clinical …

Castleman disease (CD) describes a group of heterogeneous hematologic disorders with
characteristic histopathological features. CD can present with unicentric or multicentric …

Abstract Human herpesvirus-8 (HHV-8)–negative, idiopathic multicentric Castleman disease
(iMCD) is a rare and life-threatening disorder involving systemic inflammatory symptoms …

Summary Background Multicentric Castleman's disease is a rare lymphoproliferative
disorder driven by dysregulated production of interleukin 6. No randomised trials have been …

Summary Background Multicentric Castleman's disease describes a group of poorly
understood lymphoproliferative disorders driven by proinflammatory hypercytokinaemia …

Human IL6 is a cytokine produced by many cell types that has pleiotropic effects. In
agreement, anti-IL6 therapy reduces inflammation, hepatic acute phase proteins, and …

Kaposi sarcoma (KS) herpesvirus (KSHV), also known as human herpesvirus 8, is the
causal agent of KS but is also pathogenetically related to several lymphoproliferative …

Multicentric Castleman disease (MCD) describes a heterogeneous group of disorders
involving systemic inflammation, characteristic lymph node histopathology, and multi‐organ …

The spectrum of Castleman disease (CD) has considerably extended since its first
description in 1956. Recently, an international collaborative working group has reached …

TAFRO syndrome is a systemic inflammatory disorder characterized by thrombocytopenia,
anasarca including pleural effusion and ascites, fever, renal insufficiency, and …