Heart failure remains a continuing threat to patients with chronic kidney disease (CKD).
Although various heart failure biomarkers have been applied for early detection, diagnosis …

Human growth differentiation factor 15 (GDF-15) is a widely distributed protein that has
shown to play multiple roles in both physiological and pathological conditions. In healthy …

The ageing process is accompanied by the gradual development of chronic systemic
inflammation (inflamm-ageing). Growth differentiation factor 15 (GDF15) is associated with …

Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

Background: Studies on serially measured GDF-15 (growth differentiation factor 15) in acute
heart failure (HF) are limited. Moreover, several pathophysiological pathways contribute to …

Abdominal aortic aneurysm (AAA) is increasing due to aging of the population and is a
major cause of death among the elderly. Ultrasound screening programs are useful in early …

The use of molecular biomarkers for the early detection of heart disease, before their onset
of symptoms, is an attractive novel approach. Ideal molecular biomarkers, those that are …

Mechanical stress plays a critical role among development, functional maturation, and
pathogenesis of pulmonary tissues, especially for the alveolar epithelial cells and vascular …

GDF-15 is an essential member of the transforming growth factor-beta superfamily. Its
functions mainly involve in tissue injury, inflammation, fibrosis, regulation of appetite and …

Weight gain and obesity are global health concerns contributing to morbidity with increased
risks of cardiovascular disease, diabetes, liver steatohepatitis and cancer. Pharmacological …