Efficiency, capacity, compensation, maintenance, plasticity: emerging concepts in cognitive reserve

D Barulli, Y Stern - Trends in cognitive sciences, 2013 - cell.com
Cognitive reserve (CR) is a concept meant to account for the frequent discrepancy between
an individual's measured level of brain pathology and her expected cognitive performance. It …

The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline

HIL Jacobs, DA Hopkins, HC Mayrhofer, E Bruner… - Brain, 2018 - academic.oup.com
The cerebellum has long been regarded as essential only for the coordination of voluntary
motor activity and motor learning. Anatomical, clinical and neuroimaging studies have led to …

Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders

EM Arenaza-Urquijo, B Landeau, R La Joie, K Mevel… - Neuroimage, 2013 - Elsevier
More educated elders are less susceptible to age-related or pathological cognitive changes.
We aimed at providing a comprehensive contribution to the neural mechanism underlying …

The default mode network in healthy aging and Alzheimer′ s disease

K Mevel, G Chételat, F Eustache… - International journal of …, 2011 - Wiley Online Library
In the past decade, a “default mode network”(DMN) has been highlighted in neuroimaging
studies as a set of brain regions showing increased activity in task‐free state compared to …

[HTML][HTML] Imaging the default mode network in aging and dementia

A Hafkemeijer, J Van Der Grond… - Biochimica et Biophysica …, 2012 - Elsevier
Although in the last decade brain activation in healthy aging and dementia was mainly
studied using task-activation fMRI, there is increasing interest in task-induced decreases in …

The adaptive aging brain

L Aron, J Zullo, BA Yankner - Current opinion in neurobiology, 2022 - Elsevier
The aging brain is shaped by many structural and functional alterations. Recent cross-
disciplinary efforts have uncovered powerful and integrated adaptive mechanisms that …

Toward systems neuroscience in mild cognitive impairment and Alzheimer's disease: A meta‐analysis of 75 fMRI studies

HJ Li, XH Hou, HH Liu, CL Yue, Y He… - Human brain …, 2015 - Wiley Online Library
Most of the previous task functional magnetic resonance imaging (fMRI) studies found
abnormalities in distributed brain regions in mild cognitive impairment (MCI) and Alzheimer's …

Cognitive reserve and lifestyle: moving towards preclinical Alzheimer's disease

EM Arenaza-Urquijo, M Wirth… - Frontiers in aging …, 2015 - frontiersin.org
The large majority of neuroimaging studies in Alzheimer's disease (AD) patients have
supported the idea that lifestyle factors may protect against the clinical manifestations of AD …

Education amplifies brain atrophy effect on cognitive decline: implications for cognitive reserve

D Mungas, B Gavett, E Fletcher, ST Farias… - Neurobiology of …, 2018 - Elsevier
Level of education is often regarded as a proxy for cognitive reserve in older adults. This
implies that brain degeneration has a smaller effect on cognitive decline in those with more …

Aging in autism spectrum disorders: A mini-review

F Happé, RA Charlton - Gerontology, 2011 - karger.com
This article addresses an important and barely researched topic: what happens to children
with autism spectrum disorders when they grow old. We review the small published literature …