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Internal dynamics and protein–matrix coupling in trehalose-coated proteins
We review recent studies on the role played by non-liquid, water-containing matrices on the
dynamics and structure of embedded proteins. Two proteins were studied, in water …
dynamics and structure of embedded proteins. Two proteins were studied, in water …
Thermodynamic and dynamic factors involved in the stability of native protein structure in amorphous solids in relation to levels of hydration
JJ Hill, EY Shalaev, G Zografi - Journal of pharmaceutical sciences, 2005 - Elsevier
The internal, dynamical fluctuations of protein molecules exhibit many of the features typical
of polymeric and bulk small molecule glass forming systems. The response of a protein's …
of polymeric and bulk small molecule glass forming systems. The response of a protein's …
Beneficial effects of trehalose and gentiobiose on human sperm cryopreservation
The protection of human sperm during cryopreservation is of great importance to infertility.
Recent studies have shown that this area is still a long way from its ultimate aim of …
Recent studies have shown that this area is still a long way from its ultimate aim of …
How do trehalose, maltose, and sucrose influence some structural and dynamical properties of lysozyme? Insight from molecular dynamics simulations
A Lerbret, P Bordat, F Affouard, A Hédoux… - The Journal of …, 2007 - ACS Publications
The influence of three well-known disaccharides, namely, trehalose, maltose, and sucrose,
on some structural and dynamical properties of lysozyme has been investigated by means of …
on some structural and dynamical properties of lysozyme has been investigated by means of …
Interaction of the sugars trehalose, maltose and glucose with a phospholipid bilayer: a comparative molecular dynamics study
CS Pereira, PH Hünenberger - The Journal of Physical Chemistry …, 2006 - ACS Publications
Molecular dynamics simulations are used to investigate the interaction of the sugars
trehalose, maltose, and glucose with a phospholipid bilayer at atomic resolution …
trehalose, maltose, and glucose with a phospholipid bilayer at atomic resolution …
Structural and dynamical characteristics of trehalose and sucrose matrices at different hydration levels as probed by FTIR and high-field EPR
M Malferrari, A Nalepa, G Venturoli, F Francia… - Physical Chemistry …, 2014 - pubs.rsc.org
Some organisms can survive complete dehydration and high temperatures by adopting an
anhydrobiotic state in which the intracellular medium contains large amounts of …
anhydrobiotic state in which the intracellular medium contains large amounts of …
Mechanism of trehalose-induced protein stabilization from neutron scattering and modeling
The sugar molecule trehalose has been proven to be an excellent stabilizing cosolute for the
preservation of biological materials. However, the stabilizing mechanism of trehalose has …
preservation of biological materials. However, the stabilizing mechanism of trehalose has …
Proteins in saccharides matrices and the trehalose peculiarity: Biochemical and biophysical properties
Immobilization of proteins and other biomolecules in saccharide matrices leads to a series of
peculiar properties that are relevant from the point of view of both biochemistry and …
peculiar properties that are relevant from the point of view of both biochemistry and …
Role of residual water hydrogen bonding in sugar/water/biomolecule systems: a possibleexplanation for trehalose peculiarity
L Cordone, G Cottone, S Giuffrida - Journal of Physics …, 2007 - iopscience.iop.org
We report on the set of experimental and simulative evidences which enabled us to suggest
how biological structures embedded in a non-liquid water–saccharide solvent are anchored …
how biological structures embedded in a non-liquid water–saccharide solvent are anchored …
[HTML][HTML] Trehalose matrix effects on charge-recombination kinetics in Photosystem I of oxygenic photosynthesis at different dehydration levels
Matrix effects on long-range electron transfer were studied in cyanobacterial Photosystem I
(PS I) complexes, embedded into trehalose glasses at different hydration levels. W-band …
(PS I) complexes, embedded into trehalose glasses at different hydration levels. W-band …