Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein
family members. It plays an essential role in inflammation and immunity by regulating the …

Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Macrophages have diverse phenotypes and functions due to differences in their origin,
location and pathophysiological context. Although their main role in the liver has been …

Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …

Macrophages play a central role in the development of atherosclerotic cardiovascular
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …

Dendritic cells are powerful antigen-presenting cells that are essential for the priming of T
cell responses. In addition to providing T-cell-receptor ligands and co-stimulatory molecules …

Novel experimental approaches such as fate-map** and single-cell analysis have brought
fresh insight into monocyte development and function over the past decade and helped …

Monocytes are innate immune cells of the mononuclear phagocyte system that have
emerged as important regulators of cancer development and progression. Our …

Monocytes are innate blood cells that maintain vascular homeostasis and are early
responders to pathogens in acute infections. There are three well-characterized classes of …

Monocytes develop in the bone marrow and represent the primary type of mononuclear
phagocyte found in the blood. They were long thought of as a source for tissue …