An increasing prevalence of early childhood adversity has reached epidemic proportions,
creating a public health crisis. Rather than focusing only on adverse childhood experiences …

Affective disorders are a group of neuropsychiatric disorders characterized by severe mood
dysregulations accompanied by sleep, eating, cognitive, and attention disturbances, as well …

Now astrocytes appear to be the key contributors to the pathophysiology of major
depression. Evidence in rodents shows that chronic stress is associated with a decreased …

This study was designed to investigate stressful social experience (SSE) in early life by
examining how it can induce alterations in the microbiota-gut-brain axis. To test this, different …

Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …

Stress is a major risk factor for psychiatric disorders. During and after exposure to stressors,
the stress response may have pro-or maladaptive consequences, depending on several …

Neuropsychiatric disorders, including autism spectrum disorders (ASD) and anxiety
disorders are characterized by a complex range of symptoms, including social behaviour …

MicroRNAs as critical regulators of gene expression important for functions including
neuronal development, synapse formation, and synaptic plasticity have been linked with the …

Vincristine is a widely used chemotherapeutic drug for the treatment of multiple malignant
diseases that causes a dose-limiting peripheral neurotoxicity. There is no clinically effective …

There is increasing evidence that abnormalities in epigenetic mechanisms of gene
expression contribute to the pathogenesis of anxiety disorders (ADs). This article discusses …