Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank
Abstract The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private–public
partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that …
partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that …
Premature ovarian insufficiency: past, present, and future
Premature ovarian insufficiency (POI) is the loss of normal ovarian function before the age of
40 years, a condition that affects approximately 1% of women under 40 years old and 0.1 …
40 years, a condition that affects approximately 1% of women under 40 years old and 0.1 …
[BOOK][B] Clinical gynecologic endocrinology and infertility
L Speroff, MA Fritz - 2005 - books.google.com
Established as one of the world's most widely read gynecology texts, Clinical Gynecologic
Endocrinology and Infertility is now in its Seventh Edition. In a clear, user-friendly style …
Endocrinology and Infertility is now in its Seventh Edition. In a clear, user-friendly style …
Initial and cyclic recruitment of ovarian follicles
Mammalian ovaries consist of follicles as basic functional units. The total number of ovarian
follicles is determined early in life, and the depletion of this pool leads to reproductive …
follicles is determined early in life, and the depletion of this pool leads to reproductive …
The roles of luteinizing hormone, follicle-stimulating hormone and testosterone in spermatogenesis and folliculogenesis revisited
Spermatogenesis and folliculogenesis involve cell–cell interactions and gene expression
orchestrated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH). FSH …
orchestrated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH). FSH …
[BOOK][B] Chromosome abnormalities and genetic counseling
RJMK Gardner, GR Sutherland, LG Shaffer - 2012 - books.google.com
Chromosome abnormalities have been known for over 50 years, though the methods of
analysis have become increasing more sophisticated and precise. Surprisingly, the …
analysis have become increasing more sophisticated and precise. Surprisingly, the …
Primary ovarian insufficiency
LM Nelson - New England Journal of Medicine, 2009 - Mass Medical Soc
A 30-year-old woman presents with a history of no menses since she stopped taking oral
contraceptives 6 months ago in order to conceive. She had undergone normal puberty, with …
contraceptives 6 months ago in order to conceive. She had undergone normal puberty, with …
Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility
TR Kumar, Y Wang, N Lu, MM Matzuk - Nature genetics, 1997 - nature.com
Follicle stimulating hormone (FSH) is a member of the glycoprotein hormone family that
includes luteinizing hormone (LH), thyroid stimulating hormone, and chorionic gonadotropin …
includes luteinizing hormone (LH), thyroid stimulating hormone, and chorionic gonadotropin …
Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice
SY Jiao, YH Yang, SR Chen - Human reproduction update, 2021 - academic.oup.com
BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …
Interactions between androgens, FSH, anti-Müllerian hormone and estradiol during folliculogenesis in the human normal and polycystic ovary
D Dewailly, G Robin, M Peigne… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Androgens, FSH, anti-Müllerian hormone (AMH) and estradiol (E2) are
essential in human ovarian folliculogenesis. However, the interactions between these four …
essential in human ovarian folliculogenesis. However, the interactions between these four …