Recombinant proteins are becoming increasingly important for industrial applications, where
Escherichia coli is the most widely used bacterial host for their production. However, the …

Protein aggregation occurs as a consequence of perturbations in protein homeostasis that
can be triggered by environmental and cellular stresses. The accumulation of protein …

Bacterial membrane barrier provides a cytoplasmic environment for organelles of bacteria.
The membrane is composed of lipid compounds containing phosphatide protein and a …

Recombinant proteins expressed as bacterial inclusion bodies (IBs) are now receiving
tremendous attention for many diverse applications in the areas of industrial and medical …

First designed and published in 1998 as a laboratory tool to study Myc perturbation,
Omomyc has come a long way in the past 22 years. This dominant negative has contributed …

The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

Among inorganic materials, divalent cations modulate thousands of physiological processes
that support life. Their roles in protein assembly and aggregation are less known, although …

In industry, enzymes are often immobilized to generate more stable enzyme preparations
that are easier to store, handle, and recycle for repetitive use. Traditionally, enzymes are …

Hexahistidine-tagged proteins can be clustered by divalent cations into self-containing,
dynamic protein depots at the microscale, which under physiological conditions leak …

Among bio-inspired protein materials, secretory protein microparticles are of clinical interest
as self-contained, slow protein delivery platforms that mimic secretory granules of the human …