Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis

A Booth, AB Reed, S Ponzo, A Yassaee, M Aral… - PloS one, 2021 - journals.plos.org
Aim COVID-19 clinical presentation is heterogeneous, ranging from asymptomatic to severe
cases. While there are a number of early publications relating to risk factors for COVID-19 …

COVID-19 and liver disease: mechanistic and clinical perspectives

T Marjot, GJ Webb, AS Barritt IV, AM Moon… - Nature reviews …, 2021 - nature.com
Our understanding of the hepatic consequences of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection and its resultant coronavirus disease 2019 (COVID …

[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …

[HTML][HTML] Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million …

U Agrawal, S Bedston, C McCowan, J Oke, L Patterson… - The Lancet, 2022 - thelancet.com
Background Current UK vaccination policy is to offer future COVID-19 booster doses to
individuals at high risk of serious illness from COVID-19, but it is still uncertain which groups …

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study

J Hippisley-Cox, CAC Coupland, N Mehta, RH Keogh… - bmj, 2021 - bmj.com
Objectives To derive and validate risk prediction algorithms to estimate the risk of covid-19
related mortality and hospital admission in UK adults after one or two doses of covid-19 …

Associations between body-mass index and COVID-19 severity in 6· 9 million people in England: a prospective, community-based, cohort study

M Gao, C Piernas, NM Astbury… - The lancet Diabetes & …, 2021 - thelancet.com
Background Obesity is a major risk factor for adverse outcomes after infection with SARS-
CoV-2. We aimed to examine this association, including interactions with demographic and …

Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study

J Hippisley-Cox, M Patone, XW Mei, D Saatci, S Dixon… - bmj, 2021 - bmj.com
Objective To assess the association between covid-19 vaccines and risk of
thrombocytopenia and thromboembolic events in England among adults. Design Self …

Severity of omicron variant of concern and effectiveness of vaccine boosters against symptomatic disease in Scotland (EAVE II): a national cohort study with nested …

A Sheikh, S Kerr, M Woolhouse… - The Lancet Infectious …, 2022 - thelancet.com
Background Since its emergence in November, 2021, in southern Africa, the SARS-CoV-2
omicron variant of concern (VOC) has rapidly spread across the world. We aimed to …

First-dose ChAdOx1 and BNT162b2 COVID-19 vaccines and thrombocytopenic, thromboembolic and hemorrhagic events in Scotland

CR Simpson, T Shi, E Vasileiou, SV Katikireddi… - Nature medicine, 2021 - nature.com
Reports of ChAdOx1 vaccine–associated thrombocytopenia and vascular adverse events
have led to some countries restricting its use. Using a national prospective cohort, we …

Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland

SJ McGurnaghan, A Weir, J Bishop… - The lancet Diabetes & …, 2021 - thelancet.com
Background We aimed to ascertain the cumulative risk of fatal or critical care unit-treated
COVID-19 in people with diabetes and compare it with that of people without diabetes, and …