Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the
potential to affect vision, and can even be fatal in some children. While the tumor can be …

Retinoblastoma (Rb) is known as one of important childhood malignancies which due to
inactivation of the RB gene (tumor suppressor gene in various patients). The early detection …

MicroRNAs (miRNAs) are small and highly conserved non‐coding RNAs that silence target
mRNAs, and compelling evidence suggests that they play an essential role in the …

Dysregulated metabolism is a common feature of cancer cells and is considered a hallmark
of cancer. Altered tumor-metabolism confers an adaptive advantage to cancer cells to fulfill …

To adapt to the tumor environment or to escape chemotherapy, cancer cells rapidly
reprogram their metabolism. The hallmark biochemical phenotype of cancer cells is the shift …

Retinoblastoma (RB) is the most common type of intraocular malignancy in children. During
RB oncogenesis, sonic hedgehog (SHH) is commonly differentially expressed. Additionally …

Retinoblastoma is a rare type of eye cancer of the retina that commonly occurs in early
childhood and mostly affects the children before the age of 5. It occurs due to the mutations …

MicroRNAs, as a major type of noncoding RNAs, have crucial roles in various functions
during development. Available data have shown that miR-542-3p decreased in various …

Retinoblastoma (RB) is the most common intraocular malignancy of childhood caused by
inactivation of the Rb genes. The prognosis of RB is better with an earlier diagnosis. Many …

Several lines of evidence highlight the important application of human spermatogonial stem
cells (SSCs) in translational medicine. The fate decisions of SSCs are mainly mediated by …