MicroRNA-mediated epigenetic regulation of rheumatoid arthritis susceptibility and pathogenesis

C Chang, L Xu, R Zhang, Y **, P Jiang, K Wei… - Frontiers in …, 2022 - frontiersin.org
MicroRNAs (miRNAs) play crucial roles in regulating the transcriptome and development of
rheumatoid arthritis (RA). Currently, a comprehensive map illustrating how miRNAs regulate …

Saliva and oral diseases

E Martina, A Campanati, F Diotallevi… - Journal of clinical …, 2020 - mdpi.com
Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport …

Integrative analysis of risk factors for immune-related adverse events of checkpoint blockade therapy in cancer

C Sung, J An, S Lee, J Park, KS Lee, IH Kim, JY Han… - Nature Cancer, 2023 - nature.com
Immune-related adverse events (irAEs) induced by checkpoint inhibitors involve a multitude
of different risk factors. Here, to interrogate the multifaceted underlying mechanisms, we …

[HTML][HTML] Academic Textbook: The Role of Melatonin in Pathogenesis and Treatment of Autoimmune Diseases

SOH Tabatabaei, R Moazamiyanfar, AM Fard… - Kindle, 2022 - preferpub.org
An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

Epigenetic regulation (including micro-RNAs, DNA methylation and histone modifications) of rheumatoid arthritis: a systematic review

M Payet, F Dargai, P Gasque, X Guillot - International Journal of …, 2021 - mdpi.com
The inflammatory reaction in rheumatoid arthritis (RA) is controlled by major epigenetic
modifications that modulate the phenotype of synovial and immune cells. The aim of this …

[HTML][HTML] Defining the role of monocytes in Sjögren's syndrome

JM Sequí-Sabater, L Beretta - International Journal of Molecular Sciences, 2022 - mdpi.com
Sjögren's syndrome is one of the most prevalent autoimmune diseases after rheumatoid
arthritis, with a preference for middle age, and is characterised by exocrine glandular …

Role of chemokines CXCL9, CXCL10, CXCL11, and CXCR3 in the serum and minor salivary gland tissues of patients with Sjögren's syndrome

JW Kim, MH Ahn, JY Jung, CH Suh, JH Han… - Clinical and Experimental …, 2024 - Springer
This study aimed to investigate the serum and expression levels of CXC motif chemokine
ligand 9 (CXCL9), CXCL10, CXCL11, and CXC receptor 3 (CXCR3) in minor salivary glands …

Involvement of RNA methylation modification patterns mediated by m7G, m6A, m5C and m1A regulators in immune microenvironment regulation of Sjögren's …

Y Liu, J Zhu, L Ding - Cellular Signalling, 2023 - Elsevier
Keratoconjunctivitis is the most common complication of Sjögren's syndrome (SS). It has
always been a hot research topic due to its complex pathogenesis. A further understanding …

m6A RNA Methylation in Systemic Autoimmune Diseases—A New Target for Epigenetic-Based Therapy?

A Wardowska - Pharmaceuticals, 2021 - mdpi.com
The general background of autoimmune diseases is a combination of genetic, epigenetic
and environmental factors, that lead to defective immune reactions. This erroneous immune …

Functional significance of DNA methylation: epigenetic insights into Sjögren's syndrome

Y Wang, F Riaz, W Wang, J Pu, Y Liang, Z Wu… - Frontiers in …, 2024 - frontiersin.org
Sjögren's syndrome (SjS) is a systemic, highly diverse, and chronic autoimmune disease
with a significant global prevalence. It is a complex condition that requires careful …